Could a water shot beat morphine for kidney stone pain?
NCT ID NCT07378904
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares a simple sterile water injection into the skin with intravenous morphine for relieving severe kidney stone pain. 150 adults with confirmed stones and high pain levels will receive either one or four water injections or morphine. Pain is measured over 90 minutes to see if the water approach works as well as the drug.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
sterile water injection
What this could lead to
If it works, this could offer a safe, low-cost, needle-based alternative to opioids for rapid kidney stone pain relief.
What could go wrong
This is a small, early-stage trial with 150 participants, and the effect may not match morphine's pain relief. Results may not apply to all patients.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Habib Thameur Teaching Hospital
Tunis, Tunis Governorate, 1008, Tunisia