Can your genes predict kidney stones? mayo clinic launches huge study

NCT ID NCT01127854

ENROLLING_BY_INVITATION Knowledge-focused Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study from Mayo Clinic looks at whether certain gene variants make people more likely to form calcium oxalate kidney stones. Researchers will compare 2,900 adults with and without a history of kidney stones, analyzing blood samples and lifestyle factors. The goal is to better understand genetic and environmental risks for stone formation and recurrence.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help identify people at higher genetic risk for kidney stones, leading to better prevention strategies.

What could go wrong

This is an observational study, not a treatment trial. It may not directly change patient care, and genetic findings may not apply to all populations.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Kidney Calculi nephrolithiasis nephrolithiasis, calcium oxalate urolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Mayo Clinic

    Jacksonville, Florida, 32224, United States