Tuberculous encephalopathy
MONDO:0850417A tuberculosis that is characterized by cerebral edema sometimes with features similar to acute disseminated encephalomyelitis (ADEM) and may manifest with a variety of symptoms ranging from focal neurological deficits to convulsions and decreased conscious state.
8 clinical trials for this condition and its sub-types.
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Could a common antibiotic slash deaths from brain TB?
Disease control Recruiting nowThis phase 2 trial tests whether adding the antibiotic doxycycline to standard treatment can reduce deaths and severe brain damage in adults with tuberculosis of the brain or its lining. About 200 participants will receive either doxycycline or a placebo for 8 weeks, alongside us…
Phase: PHASE2 • Sponsor: National University Hospital, Singapore • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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TB study aims to unlock secrets of the disease
Knowledge-focused Recruiting nowThis study follows 150 people with active or latent tuberculosis (TB) to collect blood, sputum, and tissue samples. The goal is to better understand how TB behaves in the body and how the immune system responds. Participants receive standard TB treatment as part of the study, but…
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Aug 18, 2026 03:00 UTC
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Blood test could revolutionize TB treatment monitoring
Knowledge-focused Recruiting nowThis study explores whether measuring tiny DNA fragments from the TB bacteria in the blood can help doctors monitor how well treatment is working. Researchers will enroll 140 adults with newly diagnosed TB in Thailand, taking blood samples over time to see if the DNA levels drop …
Sponsor: University of Oxford • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC