Blood test could revolutionize TB treatment monitoring
NCT ID NCT06845618
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study explores whether measuring tiny DNA fragments from the TB bacteria in the blood can help doctors monitor how well treatment is working. Researchers will enroll 140 adults with newly diagnosed TB in Thailand, taking blood samples over time to see if the DNA levels drop as the infection clears. If successful, this approach could replace slower, less sensitive culture tests and speed up drug development.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could provide a faster, more sensitive blood test to monitor TB treatment, helping doctors know sooner if therapy is working and aiding new drug development.
- What could go wrong
- This is an early feasibility study with only 140 participants, so results may not apply broadly. The test may not be accurate enough to replace current methods.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Shoklo Malaria Research Unit (SMRU)
RECRUITINGTak, Thailand
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