Blood test could revolutionize TB treatment monitoring

NCT ID NCT06845618

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study explores whether measuring tiny DNA fragments from the TB bacteria in the blood can help doctors monitor how well treatment is working. Researchers will enroll 140 adults with newly diagnosed TB in Thailand, taking blood samples over time to see if the DNA levels drop as the infection clears. If successful, this approach could replace slower, less sensitive culture tests and speed up drug development.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could provide a faster, more sensitive blood test to monitor TB treatment, helping doctors know sooner if therapy is working and aiding new drug development.

What could go wrong

This is an early feasibility study with only 140 participants, so results may not apply broadly. The test may not be accurate enough to replace current methods.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

extrapulmonary tuberculosis pulmonary tuberculosis tuberculosis Tuberculosis, Extrapulmonary

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Shoklo Malaria Research Unit (SMRU)

    RECRUITING

    Tak, Thailand

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••