Thromboangiitis obliterans
MONDO:0008889A rare inflammatory non-necrotizing vascular disease affecting the small- and medium-sized arteries and veins of the upper and lower extremities characterized by endarteritis and vaso-occlusion due to occlusive thrombus development. The development and progression of the disease is consistently associated with exposure to tobacco.
Also known as: Buerger's Disease, Buerger's disease, thromboangiitis obliterans, thromboangiitis obliterans [Buerger's disease], BUERGER disease, TAO, inflammatory occlusive peripheral vascular disease, occlusive peripheral vascular disease
8 clinical trials for this condition and its sub-types.
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Massive new registry tracks Drug-Coated devices in real patients
Disease control Recruiting nowThis study is collecting information from 5,000 people with peripheral vascular disease who are being treated with Boston Scientific drug-eluting devices in everyday medical practice. The goal is to see how well these devices work and how safe they are in a wide range of patients…
Sponsor: Boston Scientific Corporation • Aim: Disease control
Last updated Jul 19, 2026 00:00 UTC
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Stem cell shot aims to save limbs in rare artery disease
Disease control Recruiting nowThis study is testing whether injections of Stempeucel, a stem cell product made from donor bone marrow, can help people with critical limb ischemia caused by Buerger's disease. The goal is to see if it reduces pain, heals ulcers, improves blood flow, and prevents amputation. Onl…
Phase: PHASE4 • Sponsor: Cell Biopeutics Resources Sdn Bhd • Aim: Disease control
Last updated Jun 26, 2026 15:04 UTC
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New antibody shot could trap nicotine in smokers
Symptom relief Recruiting nowThis early-stage study tests a new drug called ATI-1013 in 15 healthy smokers. The drug is an antibody designed to bind to nicotine in the body. The main goal is to check safety and see how long the drug stays in the system. Participants get one IV dose of the drug or a placebo a…
Phase: PHASE1 • Sponsor: Antidote Therapeutics, Inc • Aim: Symptom relief
Last updated Jun 27, 2026 07:54 UTC
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Tiny probes to unlock secrets of amputation healing
Knowledge-focused Recruiting nowThis study will use tiny probes called microdialysis to measure chemicals related to blood flow, inflammation, and antibiotics right inside the amputation stump after surgery. Researchers will compare results between diabetic and non-diabetic patients to understand why some stump…
Phase: NA • Sponsor: University of Aarhus • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Surgery black box aims to cut errors in hybrid operating rooms
Knowledge-focused Recruiting nowThis study installs a 'black box' recording system in hybrid operating rooms to capture and analyze errors during vascular procedures. Researchers will study how teamwork, leadership, and the environment affect surgical performance and patient safety. The goal is to identify high…
Sponsor: University Ghent • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC