Spinal cord disorder

This pilot study tested whether a year of monthly romosozumab injections, followed by a year of weekly alendronate pills, can improve bone health in women with chronic spinal cord injury and osteoporosis. Twelve non-ambulatory women participated. The goal was to see if this two-s…

This trial tests whether contrast-enhanced ultrasound can detect spinal cord injury during decompression surgery for chronic spinal cord compression. Researchers inject an ultrasound contrast agent before, during, and after the procedure to visualize blood flow changes in the spi…

This study tested whether a single dose of zoledronic acid, a drug already used for osteoporosis, can prevent the rapid bone loss that often follows a spinal cord injury. Researchers enrolled 60 adults who had recently lost the ability to walk due to injury. They measured changes…

This study tested a special wheelchair that lets people with spinal cord injuries stand up and move around at the same time. The goal was to see if using this chair at home and in the community helps them stand more often and feel more satisfied with their daily activities. Twent…

This study tested a new approach to help people with spinal cord injury walk better. Participants received brief sessions of mild low-oxygen air (acute intermittent hypoxia) combined with gentle electrical stimulation on the back, plus walking practice. The goal was to see if thi…

This study tested whether walking training overground with body weight support helps people with chronic spinal cord injury walk better. Fourteen participants were randomly assigned to either overground or treadmill training for four weeks. The goal was to see if the overground a…

This study explores whether magnetic resonance spectroscopy (MRS) can be used to safely evaluate spinal cord lesions. Researchers will test the technique in healthy volunteers and patients with leptomeningeal disease who are receiving radiation. The main goal is to see if MRS is …

This study tested whether a special type of MRI (called DBSI) can predict how well people recover after surgery for a compressed spinal cord. 71 patients with cervical spondylotic myelopathy had this MRI before surgery and again 2 years later. Researchers looked for imaging marke…

This study tested a new way to control a robotic arm mounted on a power wheelchair. The arm uses a camera to help guide movements, making tasks like grabbing a drink easier. 21 adults who use power wheelchairs and have trouble with everyday tasks took part. They compared the new …

This study used a special MRI technique called diffusion tensor imaging to look at the spinal cord in 40 people with cervical spondylosis (neck arthritis). The goal was to see if spinal cord structure relates to symptoms like muscle weakness or numbness. Participants underwent im…