Spermatogenic failure, Y-linked, 2
MONDO:0010767Also known as: spermatogenic failure, Y-linked, 2, spermatogenic failure, Y-linked, 2, Y-linked, spermatogenic failure, Y-linked, type 2, Azf regions, SPGFY2, azoospermia Factor regions, azoospermia, nonobstructive, Y-linked, oligospermia, nonobstructive, Y-linked
14 clinical trials for this condition and its sub-types.
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Could a blood draw help men with no sperm become fathers?
Disease control Recruiting nowThis Stanford study tests whether injecting a man's own platelet-rich plasma (PRP) into his testicles can help produce sperm. Ten men with nonobstructive azoospermia who previously failed sperm retrieval will receive the injection. Three months later, doctors will check for sperm…
Phase: NA • Sponsor: Stanford University • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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New prenatal blood test aims to detect genetic disorders without invasive procedures
Diagnosis Recruiting nowThis study is testing a new blood test that looks for fetal cells in the mother's blood to detect genetic conditions like Down syndrome. The test will be compared to standard diagnostic methods such as amniocentesis or newborn testing. The study involves 1,000 pregnant individual…
Sponsor: BillionToOne Inc. • Aim: Diagnosis
Last updated Jun 27, 2026 13:06 UTC
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Social coaching may ease anxiety and autism traits in rare chromosome conditions
Symptom relief Recruiting nowThis trial tests whether a 10-session group program called Social Management Training can improve mental health, executive function, and social skills in adults aged 16 to 69 who have sex chromosome aneuploidies (extra or missing sex chromosomes). Participants complete questionna…
Phase: PHASE1 • Sponsor: University of Oslo • Aim: Symptom relief
Last updated Jul 24, 2026 00:00 UTC
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Mitochondrial DNA mutation may be a hidden cause of male infertility
Knowledge-focused Recruiting nowThis study investigates whether a specific mitochondrial DNA variant (MT-ND1 m.3700G>A) is associated with severe male infertility, specifically conditions where sperm production is absent or extremely low. Researchers analyzed existing medical records and biological samples from…
Sponsor: The Third Affiliated Hospital of Guangzhou Medical University • Aim: Knowledge-focused
Last updated Jul 11, 2026 00:00 UTC
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Scientists probe gene behind male infertility and cystic fibrosis
Knowledge-focused Recruiting nowThis observational study aims to understand how the CFTR gene is regulated in epididymal cells, which may help explain male infertility linked to cystic fibrosis. Researchers will collect leftover tissue samples from 20 men already scheduled for surgery. No extra procedures are n…
Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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New sperm-boosting method tested in 300 men
Knowledge-focused Recruiting nowThis study tests a new lab technique called HyperSperm to see if it can make sperm move better and stay healthy. Researchers will collect semen samples from 300 men with different fertility issues and compare the new method to the standard one. The goal is to find a safer and mor…
Sponsor: Fecundis Lab SL • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC