Spermatogenic failure 3
MONDO:0011720Any azoospermia in which the cause of the disease is a mutation in the SLC26A8 gene.
Also known as: SLC26A8 azoospermia, azoospermia caused by mutation in SLC26A8, spermatogenic failure 3, spermatogenic failure type 3, SPGF3
13 clinical trials for this condition and its sub-types.
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Could a blood draw help men with no sperm become fathers?
Disease control Recruiting nowThis Stanford study tests whether injecting a man's own platelet-rich plasma (PRP) into his testicles can help produce sperm. Ten men with nonobstructive azoospermia who previously failed sperm retrieval will receive the injection. Three months later, doctors will check for sperm…
Phase: NA • Sponsor: Stanford University • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Mitochondrial DNA mutation may be a hidden cause of male infertility
Knowledge-focused Recruiting nowThis study investigates whether a specific mitochondrial DNA variant (MT-ND1 m.3700G>A) is associated with severe male infertility, specifically conditions where sperm production is absent or extremely low. Researchers analyzed existing medical records and biological samples from…
Sponsor: The Third Affiliated Hospital of Guangzhou Medical University • Aim: Knowledge-focused
Last updated Jul 11, 2026 00:00 UTC
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Scientists probe gene behind male infertility and cystic fibrosis
Knowledge-focused Recruiting nowThis observational study aims to understand how the CFTR gene is regulated in epididymal cells, which may help explain male infertility linked to cystic fibrosis. Researchers will collect leftover tissue samples from 20 men already scheduled for surgery. No extra procedures are n…
Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Can your genes explain infertility? new study seeks answers
Knowledge-focused Recruiting nowThis study aims to find genes that may cause infertility in people with non-obstructive azoospermia (low or no sperm) or primary ovarian insufficiency (early menopause). Researchers will collect saliva samples from 500 adults to look for genetic differences. No new treatments are…
Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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New sperm-boosting method tested in 300 men
Knowledge-focused Recruiting nowThis study tests a new lab technique called HyperSperm to see if it can make sperm move better and stay healthy. Researchers will collect semen samples from 300 men with different fertility issues and compare the new method to the standard one. The goal is to find a safer and mor…
Sponsor: Fecundis Lab SL • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC