Small intestinal bacterial overgrowth
MONDO:0400000The presence of excessive bacteria in the small intestine that can result from result from failure of the gastric acid barrier, failure of small intestinal motility, anatomic alterations, or impairment of systemic and local immunity.
Also known as: SIBO
19 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Can probiotics boost antibiotic success against gut bacteria overgrowth?
Disease control CompletedThis study looked at whether taking probiotic supplements alongside the antibiotic rifaximin helps people with SIBO feel better. 129 adults with bloating or constipation took either probiotics or a placebo for 3 months. The goal was to see if the combination reduced symptoms and …
Phase: NA • Sponsor: Pomeranian Medical University Szczecin • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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Which scope is safer for kids? new study compares balloon enteroscopy methods
Diagnosis CompletedThis study looked at 208 children who had a procedure called balloon enteroscopy to find problems in the small intestine. Researchers compared two types—single-balloon and double-balloon—to see which one worked better and was safer. The goal was to help doctors choose the best me…
Sponsor: Shandong University • Aim: Diagnosis
Last updated Jun 27, 2026 09:05 UTC
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Could a daily supplement soothe SIBO? small trial tests safety
Symptom relief CompletedThis pilot study tested an 8-week course of a multi-ingredient nutritional supplement (AV1PD1A) in 9 adults with hydrogen-dominant small intestinal bacterial overgrowth (SIBO). The main goal was to see if the supplement was safe and tolerable. Participants took three capsules dai…
Phase: NA • Sponsor: National University of Natural Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 12:31 UTC
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Low FODMAP diet eases gut troubles in SIBO patients
Symptom relief CompletedThis study looked at whether a low FODMAP diet (LFD) can reduce stomach symptoms and improve nutrition in people with small intestinal bacterial overgrowth (SIBO). 51 adults who had finished antibiotic treatment were split into two groups: one followed the LFD, the other ate norm…
Phase: NA • Sponsor: Warsaw University of Life Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC
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Scientists map gut bugs in double infection
Knowledge-focused CompletedThis study looked at 42 adults with both H. pylori infection and small intestinal bacterial overgrowth (SIBO). Researchers used advanced DNA and chemical tests on stool samples to map the types of gut bacteria and their byproducts. The goal was to better understand how these two …
Sponsor: Zhongshan Hospital (Xiamen), Fudan University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Breath test reveals gut bacteria changes after Weight-Loss surgery
Knowledge-focused CompletedThis study looked at how gastric bypass surgery changes the bacteria in the small intestine. Researchers measured hydrogen in the breath of 51 severely obese patients before surgery and at several points up to 2 years after. The goal was to find out how often bacterial overgrowth…
Phase: NA • Sponsor: Lille Catholic University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Capsule camera data could sharpen disease detection
Knowledge-focused CompletedThis completed observational study collected over 3,700 PillCam SB3 capsule endoscopy videos from standard care procedures. The goal was to build a large database of images showing both normal and diseased small intestine tissue. Researchers will use this data to develop and vali…
Sponsor: Medtronic - MITG • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC