Sleep disorder, initiating and maintaining sleep

This study tests whether a traditional Chinese herbal formula (Tiaoshen Anti-cancer granules) combined with cognitive behavioral therapy for insomnia (CBT-I) can improve sleep and possibly extend survival in 360 women with advanced ovarian cancer. Participants will receive either…

This study tests a sleep treatment called TranS-C, adapted for veterans with PTSD and sleep problems. The goal is to improve sleep, reduce nightmares, and help veterans function better in daily life. 182 veterans will receive either the sleep treatment or usual care to see if it …

This study tests whether a drug called gamma-hydroxybutyrate (GHB) can help intensive care patients get better deep sleep. Sleep problems are very common in the ICU and can lead to serious issues like confusion and longer recovery. The trial will give GHB or a placebo to 24 adult…

This study tests whether taking inulin (a prebiotic fiber) and spirulina (a nutrient-rich algae), alone or together, can improve sleep in adults aged 18 to 60 with chronic insomnia. Over 12 weeks, 180 participants will take one of four options: inulin, spirulina, both, or a place…

This study tests a smartphone app called BELL-001 that plays sounds in sync with your breathing to help you relax and fall asleep. Forty adults with insomnia will use the app every night for 12 weeks. Researchers will track sleep quality, mood, and safety to see if this drug-free…

This study tests a slow-release melatonin (PedPRM) in 120 children aged 6 to 18 who have anorexia nervosa and trouble sleeping. Participants take either melatonin or a placebo for 13 weeks. The goal is to see if it safely improves total sleep time and related symptoms like anxiet…

This study looks at whether adding sleep-focused treatments to standard psychiatric care can reduce suicide risk in young adults. About 90 college students with suicidal thoughts and sleep problems will be randomly assigned to one of three sleep interventions. Researchers will tr…

This study tests a smartphone app called BELL-001 that plays personalized sounds in sync with your breathing to help you relax and fall asleep. 114 adults with insomnia will use the app or a sham version nightly for 4 weeks. Researchers will measure changes in sleep quality and d…