Short bowel syndrome
MONDO:0015183Short bowel syndrome is an intestinal failure due to either a congenital defect, intestinal infarction or extensive surgical resection of the intestinal tract that results in a functional small intestine of less than 200cm in length and is characterized by diarrhea, nutrient malabsoption, bowel dilation and dysmobility.
Also known as: short gut syndrome
38 clinical trials for this condition and its sub-types.
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Broader categories
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Growth hormone shows promise for weaning kids off IV nutrition
Disease control CompletedThis study tested whether giving growth hormone to children with short bowel syndrome could help them reduce or stop needing IV nutrition. Fourteen children aged 3-18 who had been on IV nutrition for at least 3 years took part. The results will show if the hormone improves intest…
Phase: PHASE3 • Sponsor: Hospices Civils de Lyon • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Fish oil treatment shows promise for liver disease in kids on IV feeding
Disease control CompletedThis study tested a fish oil emulsion called Omegaven to treat liver disease in 36 children who depend on long-term intravenous (IV) nutrition. The goal was to lower bilirubin levels, a sign of liver damage. The treatment aims to control the disease and improve liver function.
Phase: PHASE3 • Sponsor: Kapiolani Medical Center For Women & Children • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
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Simple drug may cut infection risk after major gut surgery
Disease control CompletedThis study tested whether tranexamic acid, a drug that helps blood clot, can lower the chance of infection after gastrointestinal surgery. Over 3,300 adults at higher risk for complications took part. The goal was to see if the drug reduces surgical site infections compared to a …
Phase: PHASE4 • Sponsor: Bayside Health • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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Could fiber be the key to better gut health for short bowel patients?
Disease control CompletedThis completed study looked at whether specific dietary fibers can improve nutrition and gut barrier function in people with short bowel syndrome. Ten adults with type II or III short bowel syndrome took dietary fiber, and researchers measured changes in blood and stool samples. …
Phase: NA • Sponsor: Jinling Hospital, China • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Daily injection could free kids from IV nutrition dependency
Disease control CompletedThis study tested a daily injection called teduglutide (Revestive) in 25 children aged 2 to 18 with short bowel syndrome who rely on IV nutrition. The goal was to see if the drug helps their intestines absorb more nutrients, so they can reduce or stop IV feedings. Researchers mea…
Phase: PHASE4 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Jun 26, 2026 15:47 UTC
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Can an online wellness program ease anxiety in chronic disease?
Symptom relief CompletedThis study tested a 12-week online mind-body program for adults with chronic conditions like heart failure, cancer, and liver disease. The program included mindful movement, meditation, breathwork, and coping skills. Researchers measured changes in anxiety, depression, fatigue, a…
Phase: NA • Sponsor: University of Alberta • Aim: Symptom relief
Last updated Jun 27, 2026 12:31 UTC
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Scientists map gut hormone changes after bowel surgery
Knowledge-focused CompletedThis study looked at how removing parts of the small intestine affects gut hormone levels after eating. Researchers measured these hormones in 39 people with different types of bowel resection and compared them to healthy controls. The goal was to better understand digestion and …
Phase: NA • Sponsor: Rigshospitalet, Denmark • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Nighttime feeding vs daytime: which is better for sleep and sugar levels?
Knowledge-focused CompletedThis study looked at 20 adults with short bowel syndrome who rely on home parenteral nutrition. Researchers compared giving the nutrition overnight versus during the day to see if timing affects blood sugar levels and sleep quality. Participants wore glucose monitors and activity…
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC