New weekly shot shows promise for bowel disorder patients

NCT ID NCT04881825

First seen Feb 02, 2026 · Last updated May 15, 2026 · Updated 17 times

Summary

This study tests the long-term safety and effectiveness of a weekly injection called glepaglutide in adults with short bowel syndrome, a condition where the body can't absorb nutrients properly. About 129 people who completed a prior trial will receive the drug for 2 years. The goal is to see if the treatment remains safe and continues to help manage the condition over time.

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Contacts and locations

Locations

  • Asklepios Kliniken Hamburg GmbH

    Hamburg, Germany

  • Centre Hospitalier Lyon-Sud

    Pierre-Bénite, France

  • Charité - Universitätsmedizin Berlin

    Berlin, Germany

  • Georgetown University Medical Center

    Washington D.C., District of Columbia, 20007, United States

  • Hôpital Beaujon

    Clichy, France

  • Mayo Clinic College of Medicin

    Rochester, Minnesota, 55905, United States

  • Norfolk and Norwich University Hospitals

    Norwich, United Kingdom

  • Rigshospitalet

    Copenhagen, Denmark

  • St Mark's Hospital

    Harrow, United Kingdom

  • Szpital Skawina sp. z o.o. im. Stanley Dudricka

    Skawina, Poland

  • UCLH Foundation NHS Trust

    London, United Kingdom

  • UMC Radboud Nijmegen

    Nijmegen, Netherlands

  • Universitair Ziekenhuis Leuven

    Leuven, Belgium

  • University of Nebraska Medical Center

    Omaha, Nebraska, 68198, United States

  • Universitätsklinikum Bonn

    Bonn, 53127, Germany

  • Universitätsklinikum Frankfurt

    Frankfurt, Germany

  • Universitätsmedizin Rostock

    Rostock, Germany

  • Vanderbilt University Medical Center, Nashville

    Nashville, Tennessee, 68198-3285, United States

  • Wojewodzki Specjalistyczny Szpital im. M. Pirogowa w Lodzi

    Lodz, Poland

Conditions

Explore the condition pages connected to this study.