New weekly shot shows promise for gut disorder patients
NCT ID NCT04881825
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests the long-term safety and effectiveness of a weekly injection called glepaglutide in adults with short bowel syndrome, a condition where the body cannot absorb nutrients properly. Participants who completed a previous trial will receive the drug for about 2 years. The goal is to see if the treatment remains safe and continues to help manage the condition.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Asklepios Kliniken Hamburg GmbH
Hamburg, Germany
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Centre Hospitalier Lyon-Sud
Pierre-Bénite, France
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Charité - Universitätsmedizin Berlin
Berlin, Germany
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Georgetown University Medical Center
Washington D.C., District of Columbia, 20007, United States
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Hôpital Beaujon
Clichy, France
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Mayo Clinic College of Medicin
Rochester, Minnesota, 55905, United States
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Norfolk and Norwich University Hospitals
Norwich, United Kingdom
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Rigshospitalet
Copenhagen, Denmark
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St Mark's Hospital
Harrow, United Kingdom
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Szpital Skawina sp. z o.o. im. Stanley Dudricka
Skawina, Poland
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UCLH Foundation NHS Trust
London, United Kingdom
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UMC Radboud Nijmegen
Nijmegen, Netherlands
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Universitair Ziekenhuis Leuven
Leuven, Belgium
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University of Nebraska Medical Center
Omaha, Nebraska, 68198, United States
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Universitätsklinikum Bonn
Bonn, 53127, Germany
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Universitätsklinikum Frankfurt
Frankfurt, Germany
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Universitätsmedizin Rostock
Rostock, Germany
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Vanderbilt University Medical Center, Nashville
Nashville, Tennessee, 68198-3285, United States
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Wojewodzki Specjalistyczny Szpital im. M. Pirogowa w Lodzi
Lodz, Poland
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Measuring hidden energy needs: a clue to better nutrition for gut failure patients
- Weekly shot could help people with short bowel syndrome absorb more fluids
- New drug could cut IV nutrition needs for short bowel patients
- Could a Plant-Based powder cut the need for IV nutrition?
- Growth hormone shows promise for weaning kids off IV nutrition
- New drug teduglutide monitored in 250 patients with short bowel syndrome