Secondary avascular necrosis

This study tested the safety and effectiveness of eliglustat, an oral medication, in 57 children aged 2 to 17 with Gaucher disease types 1 and 3. Some children also received the standard enzyme therapy imiglucerase. Researchers measured how the drug moves through the body, side e…

This early-stage trial tested a new gene therapy called FLT201 in 10 adults with Gaucher disease type 1. The therapy uses a harmless virus to deliver a working copy of the gene that produces a missing enzyme. The main goal was to check safety and see if the treatment can boost en…

This study looked at 22 people with jaw bone damage caused by medications for osteoporosis or cancer. They all had surgery to remove the damaged bone. Half also received a gel made from their own blood (platelet-rich fibrin) placed into the wound. The goal was to see if this gel …

This study tested whether adding bone graft fibers instead of particles to a standard bone substitute leads to more new bone growth in the upper jaw. Twenty-six adults needing sinus augmentation before dental implants received both types of graft material. Researchers measured bo…

This study tested a new way to rebuild lost jaw bone using a patient's own stem cells mixed with a 3D-printed scaffold. Seven adults with missing teeth in the front of the mouth received the treatment. The goal was to see if this approach could safely create enough new bone to su…

This study measured levels of brain chemicals related to oxidative stress and inflammation in people with type 1 Gaucher disease and healthy volunteers. Researchers gave 33 participants with Gaucher disease the antioxidant N-acetylcysteine (NAC) for about 90 days to see if it cha…

This study looked at 14 men with no teeth in their lower jaw to compare two types of connectors (multiunit abutments vs. OT Equator abutments) for implant-supported dentures. The goal was to see which connector led to less bone loss around the implants over 9 months. X-rays were …