Retinal detachment
MONDO:0008375An eye emergency condition which may lead to blindness if left untreated. It is characterized by the separation of the inner retina layers from the underlying pigment epithelium. Causes include trauma, advanced diabetes mellitus, high myopia, and choroid tumors. Symptoms include sudden appearance of floaters, sudden light flushes, and blurred vision.
Also known as: detached retina, retina, detached, retinal detachment
65 clinical trials for this condition and its sub-types.
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Broader categories
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Early eye surgery may prevent retinal detachment after bleeding
Disease control CompletedThis study looked at whether early surgery (vitrectomy) or waiting with ultrasound monitoring is better for people with sudden, dense bleeding inside the eye. The goal was to see if early surgery could lower the chance of the retina detaching. Only 8 adults with recent bleeding f…
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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Eye drops before surgery may tame inflammation in retinal detachment
Disease control CompletedThis study tested whether nepafenac 0.1% eye drops, given before surgery, can lower inflammation in people with retinal detachment. Sixty-one adults used the drops or a placebo for five days before surgery. Researchers measured inflammatory markers in the eye fluid. The goal is t…
Phase: PHASE4 • Sponsor: Indonesia University • Aim: Disease control
Last updated Jun 26, 2026 15:21 UTC
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Could a tiny eye insert replace drops for kids after surgery?
Symptom relief CompletedThis early study tested a tiny dexamethasone insert placed in the tear duct of 15 children after retinal surgery or laser treatment. The goal was to see if it could safely reduce pain and eye inflammation. Researchers measured pain using a standard scale and tracked any side effe…
Phase: EARLY_PHASE1 • Sponsor: Lejla Vajzovic, MD, FASRS • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Could a tiny implant save sight in eye cancer patients?
Symptom relief CompletedThis early-phase study tested a single dexamethasone implant (Ozurdex) in 10 people with uveal melanoma who had fluid buildup under the retina after radiation treatment. The goal was to see if the implant is safe and can help reduce the fluid to prevent vision loss. The implant i…
Phase: PHASE1 • Sponsor: Ivana K. Kim • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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Soothing sounds: slow music eases anxiety during eye procedures
Symptom relief CompletedThis study tested whether playing slow tempo music before and during an eye injection (intravitreal injection) can reduce anxiety and pain. 144 adults took part, with half listening to music and the other half receiving standard care. Researchers measured anxiety using saliva tes…
Phase: NA • Sponsor: Ng Yu Siang • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
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New eye scanner aims to sharpen view of retinal disease
Knowledge-focused CompletedThis trial tests a new device called P200TxE that takes detailed images of the back of the eye. Researchers want to see how well it captures images in people with retinal diseases like glaucoma or macular degeneration. The study involves adults aged 22 and older who have been dia…
Phase: NA • Sponsor: Optos, PLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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AI boosts eye Doctors' accuracy in reading retinal scans?
Knowledge-focused CompletedThis study tested whether artificial intelligence (AI) can help doctors detect retinal diseases from ultra-widefield eye images. 462 images were read by four eye doctors with different experience levels, both with and without AI assistance. The goal was to see if AI improves accu…
Sponsor: Xiamen Ophthalmology Center Affiliated to Xiamen University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Does the type of eye tamponade affect retinal shift after detachment repair?
Knowledge-focused CompletedThis study looked at 78 people in Pakistan who had surgery for a detached retina. Doctors compared two types of fillers used inside the eye after surgery—gas or silicone oil—to see if one caused more shifting of the retina afterward. The goal was to learn how the choice of filler…
Phase: NA • Sponsor: Wardah • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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Nearsighted patients studied for retinal detachment risk after cataract surgery
Knowledge-focused CompletedThis study followed 609 nearsighted adults who had lens surgery to see if a natural eye change called posterior vitreous detachment (PVD) affects their risk of retinal detachment. Participants were grouped by whether they had PVD before surgery or not, and were monitored for up t…
Sponsor: Prim. Prof. Dr. Oliver Findl, MBA • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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New study peers into the Eye's recovery after retinal detachment
Knowledge-focused CompletedThis study looked at 202 people who had surgery for retinal detachment, a condition where the light-sensitive layer at the back of the eye pulls away. Researchers used high-resolution eye scans and vision tests to see how the eye heals over a year. The goal was to better understa…
Phase: NA • Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Scientists probe eye fluids to unlock secrets of retinal detachment
Knowledge-focused CompletedThis completed study looked at fluid samples from the eyes of 137 people undergoing surgery for retinal detachment or other eye conditions. Researchers measured fats and proteins in these fluids to understand inflammation and cell death that can harm vision after surgery. The goa…
Phase: NA • Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC