Eye drops before surgery may tame inflammation in retinal detachment
NCT ID NCT07162818
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested whether nepafenac 0.1% eye drops, given before surgery, can lower inflammation in people with retinal detachment. Sixty-one adults used the drops or a placebo for five days before surgery. Researchers measured inflammatory markers in the eye fluid. The goal is to see if this simple treatment could help prevent a complication called proliferative vitreoretinopathy (PVR), which can cause surgical failure.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Nepafenac 0.1% eye drops
What this could lead to
If it works, this could point toward a simple eye drop treatment before surgery to reduce inflammation and prevent scarring in retinal detachment.
What could go wrong
This is a small, early-phase study measuring biomarkers, not clinical outcomes. The drops may not actually prevent vision loss or scarring in real-world use.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Department of Ophthalmology, Faculty of Medicine Universitas Indonesia Cipto Mangunkusumo Hospital
Jakarta, Jakarta Pusat, Indonesia