Eye drops before surgery may tame inflammation in retinal detachment
NCT ID NCT07162818
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested whether nepafenac 0.1% eye drops, given before surgery, can lower inflammation in people with retinal detachment. Sixty-one adults used the drops or a placebo for five days before surgery. Researchers measured inflammatory markers in the eye fluid. The goal is to see if this simple treatment could help prevent a complication called proliferative vitreoretinopathy (PVR), which can cause surgical failure.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Nepafenac 0.1% eye drops
- What this could lead to
- If it works, this could point toward a simple eye drop treatment before surgery to reduce inflammation and prevent scarring in retinal detachment.
- What could go wrong
- This is a small, early-phase study measuring biomarkers, not clinical outcomes. The drops may not actually prevent vision loss or scarring in real-world use.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Department of Ophthalmology, Faculty of Medicine Universitas Indonesia Cipto Mangunkusumo Hospital
Jakarta, Jakarta Pusat, Indonesia
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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