Retinal detachment
MONDO:0008375An eye emergency condition which may lead to blindness if left untreated. It is characterized by the separation of the inner retina layers from the underlying pigment epithelium. Causes include trauma, advanced diabetes mellitus, high myopia, and choroid tumors. Symptoms include sudden appearance of floaters, sudden light flushes, and blurred vision.
Also known as: detached retina, retina, detached, retinal detachment
65 clinical trials for this condition and its sub-types.
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Broader categories
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Gas-Free eye surgery could revolutionize macular hole repair
Disease control OngoingThis study tests a new surgical technique to close macular holes in people with high myopia without using a gas bubble. The standard approach requires a gas bubble that blurs vision and forces patients to keep their head down for days. The new method uses a gel-like substance to …
Phase: NA • Sponsor: Chinese University of Hong Kong • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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Could peeling an extra layer during eye surgery prevent repeat detachment?
Disease control OngoingThis study compares two types of surgery for people with a detached retina. One group gets standard repair surgery, the other gets an extra step where a thin membrane is peeled away. Researchers want to see if this extra step lowers the chance of re-detachment and improves vision…
Phase: NA • Sponsor: Berner Augenklinik • Aim: Disease control
Last updated Jun 27, 2026 08:02 UTC
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Eye surgery trial to prevent blindness in stickler syndrome pulled before start
Prevention TerminatedThis study aimed to see if a surgical procedure called scleral buckling could prevent retinal detachment in people with Stickler syndrome, a genetic condition that raises the risk of vision loss. The plan was to treat one eye in patients aged 5 to 35 who had already lost vision i…
Phase: PHASE2 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Prevention
Last updated Jun 27, 2026 12:29 UTC
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AI eye scans aim to predict Sight-Threatening complication after retinal surgery
Knowledge-focused ENROLLING_BY_INVITATIONThis study investigates whether advanced eye imaging and artificial intelligence can predict proliferative vitreoretinopathy (PVR), a condition that can cause retinal detachment surgery to fail. Researchers will analyze scans from 100 patients with retinal detachment, some with P…
Sponsor: University College, London • Aim: Knowledge-focused
Last updated Jul 04, 2026 00:00 UTC
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Eye surgery silicone may change cornea cells, study finds
Knowledge-focused OngoingThis study looks at how silicone oil, used to repair detached retinas, affects the cells on the inner surface of the cornea. Researchers will measure cell density and shape changes in 40 patients at 1 and 3 months after surgery. They also want to see if any changes go away after …
Sponsor: Minia University • Aim: Knowledge-focused
Last updated Jul 02, 2026 00:00 UTC
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Eye pressure clue could sharpen vision after retinal surgery
Knowledge-focused OngoingThis study looks at whether having low eye pressure before surgery changes how well doctors can predict your final glasses prescription after a combined cataract and retinal detachment repair. Researchers will compare two groups of people: those with low eye pressure and those wi…
Phase: NA • Sponsor: Kazakh Eye Research Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Eye surgery showdown: UNITY VCS vs CONSTELLATION trial pulled
Knowledge-focused TerminatedThis study aimed to compare two surgical systems, UNITY VCS and CONSTELLATION, for treating various eye conditions like macular holes and retinal detachment. It was designed for adults needing vitreoretinal surgery. However, the trial was withdrawn before enrolling any participan…
Phase: NA • Sponsor: Alcon Research • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Free eye tests aim to catch vision loss early in harlem and washington heights
Knowledge-focused OngoingThis study offers free vision screenings to underserved adults over 40 living in affordable housing in Harlem and Washington Heights. The goal is to find eye problems like glaucoma, cataracts, and diabetic retinopathy early and connect people with follow-up care. About 749 partic…
Phase: NA • Sponsor: Columbia University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC