Cure My Disease

Don't miss your cure!

 Log in / Sign up

Could skipping Face-Down recovery be safe for macular hole surgery?

NCT ID NCT07787390

Disease control Sponsor: Lahore General Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 26, 2026 · Last updated Aug 27, 2026 · Updated 1 time

Summary

This trial tests whether people with large macular holes (over 400 micrometres) can heal without the usual face-down positioning after surgery. All participants undergo a procedure called inverted flap vitrectomy with gas tamponade, and half are asked to avoid face-down posturing while the other half follows standard positioning. The main goal is to see if the hole closes completely, as measured by imaging, and whether skipping positioning is just as effective.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Macular hole surgery with inverted internal limiting membrane flap and SF6 gas tamponade
What this could lead to
If successful, this could make recovery from macular hole surgery much easier by removing the need for uncomfortable face-down positioning.
What could go wrong
This is a small, early-stage study, and results may not apply to all patients. There is a risk that skipping face-down positioning could lower the chance of the hole closing.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

52 people

The number who actually took part.

Started

May 2026

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

52 to 84 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Gender: male and female * All patient having age between 52-84 years * All the patients with full thickness macular hole * All the patients with written informed consent Exclusion Criteria: * Patients with high myopia. * Patient having age related macular degenerations (AMD). * Patient having any chorioretinal disease or Diabetic retinopathy. * Secondary MH causes * Trauma. * Uveitis. * Cystic macular edema. * Age-related macular degeneration * Glaucoma or ocular hypertension * corneal opacity * Patient with history of previously intraocular or vitrectomy surgery other than uncomplicated cataract surgery. * Patient with history of previous laser photocoagulation. * Presence of traction on the macula (OCT). * Patient with significant media opacity preventing retinal view or poor image quality.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Macular hole are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

macular holes retinal perforation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Macular hole

Contacts and locations

Locations

  • Lahore General Hospital, Lahore

    Lahore, Punjab Province, 54000, Pakistan

More trials for these conditions

Other studies related to the condition(s) this trial covers.