Pulmonary tuberculosis
MONDO:0006052A bacterial infection that affects the lungs and is caused by Mycobacterium tuberculosis. Most patients with tuberculosis do not have symptoms (latent tuberculosis) and are not contagious. When signs and symptoms occur (active tuberculosis), patients become contagious. The signs and symptoms include chronic cough with blood-tinged sputum, night sweats, fever, fatigue, and weight loss.
Also known as: lung TB, lung tuberculosis, pulmonary TB
104 clinical trials for this condition and its sub-types.
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Broader categories
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Could a 3-Month TB cocktail replace the standard 6-Month regimen?
Disease control TerminatedThis clinical trial investigates whether a 3-month combination of clofazimine and rifapentine can effectively treat drug-susceptible tuberculosis (TB) compared to the standard 6-month regimen. The study includes adults with pulmonary TB, some of whom also have HIV. Researchers ar…
Phase: PHASE2 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Disease control
Last updated Jul 10, 2026 00:00 UTC
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Could aspirin or ibuprofen help beat TB faster?
Disease control TerminatedThis study tested whether adding aspirin or ibuprofen to standard tuberculosis (TB) treatment helps patients recover more quickly. It included 426 adults with drug-sensitive or drug-resistant TB. The trial was terminated early, so the results are not conclusive.
Phase: PHASE2 • Sponsor: Fundació Institut Germans Trias i Pujol • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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New TB drug cocktails aim to cut treatment time in half
Disease control TerminatedThis clinical trial tested whether combining several drugs—bedaquiline, OPC-167832, sutezolid, and either pretomanid or delamanid—could treat pulmonary tuberculosis in just 2 to 4 months instead of the standard 6 months. The study enrolled 93 adults with drug-sensitive or drug-re…
Phase: PHASE2 • Sponsor: Gates Medical Research Institute • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC