Proliferative diabetic retinopathy
MONDO:0001660Advanced retinopathy due to diabetes mellitus characterized by the formation of new vessels in the retina. The new vessels are abnormal and fragile. If hemorrhage occurs due to the vascular fragility, there is increased risk of vision loss or blindness.
36 clinical trials for this condition and its sub-types.
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Eye injection vs. surgery: which is better for diabetic retinopathy?
Disease control Recruiting nowThis study tests two ways to treat proliferative diabetic retinopathy, a serious eye problem caused by diabetes. One group gets eye injections of faricimab plus laser treatment; the other gets vitrectomy surgery with laser. Researchers will track vision and how many extra treatme…
Phase: PHASE3 • Sponsor: Jaeb Center for Health Research • Aim: Disease control
Last updated Jul 18, 2026 00:00 UTC
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Could stem cells restore sight in damaged eyes?
Disease control Recruiting nowThis study tests whether injecting a person's own bone marrow stem cells into or near the eye can help treat various retinal and optic nerve diseases, including age-related macular degeneration, retinitis pigmentosa, and glaucoma. Participants receive stem cell injections via dif…
Phase: NA • Sponsor: MD Stem Cells • Aim: Disease control
Last updated Jul 01, 2026 00:00 UTC
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Early surgery may beat laser for diabetic eye damage
Disease control Recruiting nowThis study compares two treatments for early proliferative diabetic retinopathy, a complication of diabetes that causes abnormal blood vessels in the eye. One group gets early microincision vitrectomy surgery plus laser, while the other gets standard laser therapy alone. The goal…
Phase: NA • Sponsor: Xiamen Ophthalmology Center Affiliated to Xiamen University • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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Can one laser session beat multiple for diabetic eye disease?
Disease control Recruiting nowThis study compares having one laser treatment versus several sessions for a serious diabetic eye condition that can cause blindness. Researchers want to see which approach is safer and works better. The study will involve 40 adults with type 1 or type 2 diabetes who have this ey…
Phase: NA • Sponsor: Vastra Gotaland Region • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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New eye scanner tested against gold standard for retina diagnosis
Diagnosis Recruiting nowThis study tests a new eye imaging device (VG200D OCT) that takes detailed pictures of the retina. It compares these images to standard dye-based images (FA/ICGA) to see if the new device works just as well. About 30 adults with retina problems will take part. The goal is to see …
Sponsor: Intalight, Inc • Aim: Diagnosis
Last updated Jun 27, 2026 12:29 UTC
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Super camera could catch eye diseases before they steal your sight
Diagnosis Recruiting nowThis study tests a special camera that takes detailed images of the retina using many wavelengths of light. Researchers hope it can find early signs of eye diseases like age-related macular degeneration, diabetic retinopathy, and glaucoma. About 1,000 adults in Melbourne, Austral…
Phase: NA • Sponsor: Center for Eye Research Australia • Aim: Diagnosis
Last updated Jun 27, 2026 12:24 UTC
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New eye dye could make retinal scans safer and sharper
Diagnosis Recruiting nowThis study tests a new dye called MB-102 for taking pictures of the back of the eye (retina) to diagnose conditions like diabetic retinopathy and macular degeneration. About 10 adults with healthy or diseased eyes will receive both the new dye and a standard dye to compare safety…
Phase: EARLY_PHASE1 • Sponsor: MediBeacon • Aim: Diagnosis
Last updated Jun 27, 2026 09:01 UTC
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Scientists launch eye tissue bank to unlock secrets of retinal disease
Knowledge-focused Recruiting nowThis study is creating a large collection of health information and biological samples (like blood, saliva, and eye tissue) from people with and without retinal diseases. Researchers aim to use this database to better understand conditions like age-related macular degeneration an…
Sponsor: National Eye Institute (NEI) • Aim: Knowledge-focused
Last updated Jul 02, 2026 00:00 UTC
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New eye scan study aims to catch retinal disease early
Knowledge-focused Recruiting nowThis study uses a special eye scan (OCT angiography) to take detailed pictures of blood vessels in the back of the eye. Researchers will follow about 1,050 people with retinal diseases like diabetic retinopathy and healthy volunteers to see how these images can help detect early …
Phase: NA • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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New eye camera sees cells that may unlock secrets of blindness
Knowledge-focused Recruiting nowThis study uses a special camera (adaptive optics) to take detailed pictures of the back of the eye in people with inherited retinal diseases. Researchers want to see how individual cells change over time and after treatments. About 200 participants aged 5 to 70 will be observed,…
Sponsor: The Hospital for Sick Children • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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New study aims to catch diabetic eye disease before it steals sight
Knowledge-focused Recruiting nowThis study follows 100 people with type 2 diabetes who have moderate to severe diabetic retinopathy, a condition that can lead to vision loss. Researchers will use advanced eye scans and imaging to track changes in the retina over two years. The goal is to find better ways to pre…
Sponsor: Association for Innovation and Biomedical Research on Light and Image • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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New eye scanner tested on 180 volunteers – no treatment involved
Knowledge-focused Recruiting nowThis study gathers eye scan images from 180 people with healthy eyes or eye diseases like glaucoma and retinal disease. The goal is to collect data using a new optical coherence tomography (OCT) device called A10900. No treatment or medication is given. The information will help …
Sponsor: Optos, PLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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New laser tech captures eye blood flow in unprecedented detail
Knowledge-focused Recruiting nowThis study aims to create a database of eye images using a new holographic Doppler laser device. The goal is to better visualize and measure blood flow in the retina and choroid, which is important for diagnosing eye diseases. About 123 adults, both with and without eye condition…
Sponsor: Fondation Ophtalmologique Adolphe de Rothschild • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC