Proliferative diabetic retinopathy
MONDO:0001660Advanced retinopathy due to diabetes mellitus characterized by the formation of new vessels in the retina. The new vessels are abnormal and fragile. If hemorrhage occurs due to the vascular fragility, there is increased risk of vision loss or blindness.
36 clinical trials for this condition and its sub-types.
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New drug could cut repeat eye surgeries in diabetics
Disease control ENROLLING_BY_INVITATIONThis study tests whether the drug farcimab (Vabysmo), given as an injection before and after eye surgery, can reduce bleeding complications in people with diabetes who have bleeding inside the eye. About 100 adults will receive either farcimab or a sham injection. The goal is to …
Phase: PHASE4 • Sponsor: University of Colorado, Denver • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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New hope for diabetic eyes: stronger dose may stop vision loss
Disease control OngoingThis study tests a higher dose (8mg) of aflibercept in 40 adults with proliferative diabetic retinopathy (PDR) who do not have swelling in the center of the retina. The goal is to see if this treatment can improve the severity of the disease and maintain vision over 96 weeks. Par…
Phase: PHASE4 • Sponsor: Edward Wood, MD • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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New study tests safer eye surgery for diabetics to protect vision
Disease control OngoingThis trial compares two surgical methods for diabetic patients with proliferative diabetic retinopathy who need vitrectomy. One method spares the central part of the retina (fovea), while the other removes the entire inner limiting membrane. The study will measure vision and eye …
Phase: NA • Sponsor: David Nashaat Shafik Fahmy • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Eye surgery showdown: UNITY VCS vs CONSTELLATION trial pulled
Knowledge-focused TerminatedThis study aimed to compare two surgical systems, UNITY VCS and CONSTELLATION, for treating various eye conditions like macular holes and retinal detachment. It was designed for adults needing vitreoretinal surgery. However, the trial was withdrawn before enrolling any participan…
Phase: NA • Sponsor: Alcon Research • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC