Progressive non-fluent aphasia

This study tested a ketogenic drink made from medium chain triglycerides (MCTs) in 43 people with Alzheimer's disease or a type of frontotemporal dementia. The goal was to see if it was safe and tolerable, and to measure ketone levels in the blood. It was a small, early-stage tri…

This study tested whether repeated sessions of transcranial magnetic stimulation (TMS) could improve language in people with primary progressive aphasia (PPA), a condition that slowly damages language areas of the brain. Ten participants received both real and sham (fake) TMS ove…

This pilot study tested whether combining a mild brain stimulation technique (tDCS) with intensive language therapy can help people with non-fluent aphasia after a stroke. Ten participants received both real and sham stimulation during therapy sessions. The goal was to see if the…

This study tested a video-based program called STELLA-FTD to help family caregivers of people with frontotemporal dementia (FTD). Sixteen caregivers participated in the program, which aimed to reduce their stress and improve their quality of life. The approach used videoconferenc…

This study tested speech entrainment therapy (SET) in 80 people with non-fluent aphasia after a stroke. Participants practiced speaking along with an audio-visual computer program for 3, 4.5, or 6 weeks, or received no therapy. The goal was to find the best duration for lasting i…

This study tested whether a gentle, non-invasive brain stimulation technique called tDCS, combined with language therapy, could improve speech in 23 people with primary progressive aphasia (PPA). Participants received either real or fake (sham) stimulation daily for 10 days. Rese…

This study tested whether a gentle electrical current applied to the brain (tDCS) can improve language when combined with speech therapy in people with primary progressive aphasia (PPA), a condition that slowly damages language abilities. 76 adults with two types of PPA received …

This completed study from the National Institute of Neurological Disorders and Stroke aimed to better understand how the brain controls movement and what goes wrong in movement disorders like Parkinson's disease, Tourette's syndrome, and dystonia. Over 1,200 adults—both patients …

This study investigates how different language treatments affect both language skills and brain function in people with aphasia, a condition that impairs the ability to speak, understand, read, or write after a stroke. Participants will receive therapy targeting naming, spelling,…

This completed study looked at how people learn and remember associations, like names or where you met someone. Researchers compared healthy young and older adults with patients who have memory problems from Alzheimer's or semantic dementia. They used memory tests and brain scans…

This study interviewed 26 adults who either have behavioral variant frontotemporal dementia (bvFTD) or carry a gene that puts them at risk. The goal was to learn how the condition affects daily life, emotions, and coping. No treatment or medication was tested—just listening and g…

This study surveyed 219 family caregivers of people with dementia to explore how swallowing problems (dysphagia) affect their burden and needs. Caregivers completed a one-time online questionnaire about their experiences, stress, and knowledge. The goal is to better understand an…

This study tested a wrist-worn device called the Personal KinetiGraph (PKG) to see if it can accurately measure movement problems in people with Parkinson's disease. Nineteen participants wore the device while researchers compared its readings to standard clinical tests and video…