Progressive familial heart block
MONDO:0019490A hereditary cardiac conduction disorder that may progress to complete atrioventricular (AV) block. The disease is either asymptomatic or manifests as dyspnea, dizziness, syncope, abdominal pain, heart failure or sudden death.
Also known as: familial Lenègre disease, familial Lev-Lenègre disease, familial progressive heart block, hereditary bundle branch defect, familial progressive cardiac conduction defect
51 clinical trials for this condition and its sub-types, 0 tagged with Progressive familial heart block itself.
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Browse by category →Sub-types of Progressive familial heart block
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New heart lead under watch: 5-Year safety check begins
Disease control By invitation onlyThis study follows 2000 people who have or will get the OmniaSecure defibrillation lead, a wire that helps control dangerous heart rhythms. Researchers will track how often the lead causes problems over 5 years. The goal is to make sure the lead is safe and works as expected in e…
Sponsor: Medtronic • Aim: Disease control
Last updated Aug 05, 2026 00:00 UTC
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New antibiotic pouch aims to stop infections in heart device patients
Disease control OngoingThis study is tracking 100 adults who receive an EluPro antibiotic-eluting envelope during implantation of a heart device (like a pacemaker). The envelope slowly releases antibiotics to prevent infection. Researchers are monitoring complication rates in real-world use to see how …
Sponsor: Elutia Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:39 UTC
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New heart pacing strategy could cut defibrillator need
Disease control OngoingThis study tests whether a special heart pacing technique (left bundle branch pacing) combined with standard heart failure drugs can improve heart function better than drugs alone. It includes 50 adults with non-ischemic heart failure and a specific heart block. The main goal is …
Sponsor: The First Affiliated Hospital with Nanjing Medical University • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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New pacemaker study aims to help heart failure patients with mildly reduced pumping function
Disease control OngoingThis study is testing whether a special pacemaker (cardiac resynchronization therapy, or CRT) can improve heart function and symptoms in people with mild heart failure and a specific type of heart block called left bundle-branch block. About 21 participants will receive a CRT dev…
Sponsor: Inova Health Care Services • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Heart device DiamondTemp under Real-World watch: will it deliver?
Knowledge-focused OngoingThis registry follows 545 people with arrhythmia who received a heart ablation using the DiamondTemp system. Researchers will track how many stay free of their heart rhythm problem and how many have serious side effects over 12 months. The goal is to see how well the device works…
Sponsor: Medtronic Cardiac Ablation Solutions • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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Ear zaps may tweak heart rhythms, tiny study hints
Knowledge-focused OngoingThis small pilot study is testing whether a gentle, non-invasive electrical stimulation on the ear (auricular vagus nerve stimulation) can change how the heart's electrical system works. Ten people who are already scheduled for a heart procedure will receive the stimulation while…
Sponsor: Northwell Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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Heart failure clue: blood test may forecast therapy success
Knowledge-focused OngoingThis study looks at whether a substance called YKL-40 in the blood can help predict how well heart failure patients will respond to cardiac resynchronization therapy (CRT), a special pacemaker. About 51 adults with severe heart failure will have blood samples taken during their r…
Sponsor: Trakya University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC