Progressive familial heart block
MONDO:0019490A hereditary cardiac conduction disorder that may progress to complete atrioventricular (AV) block. The disease is either asymptomatic or manifests as dyspnea, dizziness, syncope, abdominal pain, heart failure or sudden death.
Also known as: familial Lenègre disease, familial Lev-Lenègre disease, familial progressive heart block, hereditary bundle branch defect, familial progressive cardiac conduction defect
51 clinical trials for this condition and its sub-types, 0 tagged with Progressive familial heart block itself.
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Browse by category →Sub-types of Progressive familial heart block
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Which pacing target keeps the heart stronger? a trial aims to find out
Disease control Not yet recruitingThis trial tests two ways of placing a pacemaker lead in the heart's left bundle branch area. One strategy aims to directly capture the heart's conduction system, while the other accepts capture of the nearby septal muscle. Researchers will compare how well the heart's pumping fu…
Sponsor: Yonsei University • Aim: Disease control
Last updated Sep 06, 2026 00:00 UTC
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Smarter heart pacing could cut hospital stays for heart failure patients
Disease control Not yet recruitingThis study tests a newer, more natural pacing method for people with heart failure and electrical problems in the heart. The approach uses the heart's own conduction system to improve coordination between chambers. Researchers will track patients for two years to see if this meth…
Sponsor: University of Pecs • Aim: Disease control
Last updated Jul 12, 2026 00:00 UTC
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Massive heart study aims to sharpen diagnosis and cut needless hospital stays
Knowledge-focused Not yet recruitingThis study follows 25,000 people referred to a specialized heart clinic with symptoms like chest pain or shortness of breath. Researchers will track which heart conditions are actually diagnosed and how patients are evaluated. The goal is to improve diagnostic accuracy and unders…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jul 02, 2026 00:00 UTC
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Could heart and muscle disorders share a genetic cause?
Knowledge-focused Not yet recruitingThis study looks at whether people with certain heart rhythm disorders also carry genetic variants linked to a rare muscle condition called non-dystrophic myotonia. Researchers will review medical records of 570 participants and invite some for a neurological exam and electromyog…
Sponsor: Universitair Ziekenhuis Brussel • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC