New pacemaker study aims to help heart failure patients with mildly reduced pumping function
NCT ID NCT05652218
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing whether a special pacemaker (cardiac resynchronization therapy, or CRT) can improve heart function and symptoms in people with mild heart failure and a specific type of heart block called left bundle-branch block. About 21 participants will receive a CRT device and be randomly assigned to have it set to either a standard pacing mode or a newer left bundle-branch pacing mode. The main goal is to see if the device can improve a measure of heart pumping efficiency over time.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
cardiac resynchronization therapy pacemaker
What this could lead to
If successful, this could offer a new pacing option to improve heart function and reduce symptoms in patients with mild heart failure who currently have limited treatment choices.
What could go wrong
This is a very small early-phase trial with only 21 participants, so results may not apply to everyone. The device implant carries standard risks like infection or lead problems, and the benefit over existing treatments is unproven.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Duke University Medical Center
Durham, North Carolina, 27710, United States
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Inova Health System
Falls Church, Virginia, 22042, United States