Primary adrenal insufficiency

MONDO:0015128

A hormonal disorder that occurs when the adrenal glands fail to release adequate amounts of glucocorticoids (cortisol), mineralocorticoids (aldosterone, 11-deoxycorticosterone), and androgens (dehydroepiandrosterone) to meet physiologic needs, despite release of ACTH from the pituitary.

Also known as: Addison's disease

50 clinical trials for this condition and its sub-types, 5 tagged with Primary adrenal insufficiency itself.

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Where it sits in the disease tree

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Part of

↑ Adrenocortical insufficiency (76)

Sub-types of Primary adrenal insufficiency

Chronic primary adrenal insufficiency 6 trials · 47 incl. sub-types
8 sub-types
- Congenital adrenal hyperplasia 36 trials · 38 incl. sub-types Sub-types →
- Triple-A syndrome 3 trials
- X-linked adrenal hypoplasia congenita 0 trials Sub-types →
- Adrenocortical hypofunction, chronic primary congenital 0 trials
- Autoimmune primary adrenal insufficiency 0 trials
- Familial adrenal hypoplasia with absent pituitary luteinizing hormone 0 trials
- Familial glucocorticoid deficiency 0 trials Sub-types →
- Inherited isolated adrenal insufficiency due to partial CYP11A1 deficiency 0 trials
Acute adrenal insufficiency 0 trials
2 sub-types
- Waterhouse-Friderichsen syndrome 0 trials
- Bilateral massive adrenal hemorrhage 0 trials

Most studied deeper sub-types

Including sub-types (50) Tagged with Primary adrenal insufficiency (5)

Trials to join now! 1 Not yet recruiting 1 Not yet finished but already full! 2 Completed 1

Primary adrenal insufficiency

Where it sits in the disease tree

Most studied deeper sub-types

Could a Once-Daily steroid pill improve blood sugar control in Dual-Disease patients?

Do some Addison's patients still make their own hormones? new study investigates.