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Acute adrenal insufficiency

MONDO:0019801

A primary adrenal insufficiency caused by a sudden defective production of adrenal steroids (cortisol and aldosterone). It represents an emergency, thus the rapid recognition and prompt therapy are critical for survival even before the diagnosis is made.

Also known as: Addisonian crisis, acute adrenal failure, acute adrenocortical insufficiency, adrenal crisis, adrenocortical crisis

2 clinical trials for this condition and its sub-types.

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Sub-types

Bilateral massive adrenal hemorrhage (0) Waterhouse-Friderichsen syndrome (0)

Broader categories

Disease (680) Endocrine system disorder (72) Adrenocortical insufficiency (26) Acute disease (20) Human disease (14) Adrenal gland disorder (8) Primary adrenal insufficiency (4) Adrenal cortex disorder (0) Disease by body system or component (0)
Trials to join now! 1 Not yet recruiting 1
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  • New imaging tracer could shed light on adrenal cholesterol

    Knowledge-focused Recruiting now

    This study tests a special radioactive tracer called [18F]FNP-59 to see if it can safely and clearly show cholesterol activity in the adrenal gland using PET scans. About 24 people will take part, including healthy volunteers and those with known adrenal problems. The goal is to …

    Phase: EARLY_PHASE1 • Sponsor: Benjamin Viglianti • Aim: Knowledge-focused

    Last updated Jun 27, 2026 08:02 UTC

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