Do some Addison's patients still make their own hormones? new study investigates.

NCT ID NCT03793114

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how many people with Addison's disease still produce small amounts of adrenal hormones like cortisol, even years after diagnosis. Researchers will test 200 adults in Norway and Sweden using blood and urine samples. The goal is to see if this leftover function affects quality of life, work ability, medication doses, or risk of adrenal crisis.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could help doctors personalize treatment for Addison's patients based on their remaining adrenal function.

What could go wrong

This is an observational study, not a treatment trial. It will not test any new drug or therapy, so it cannot directly improve outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic primary adrenal insufficiency primary adrenal insufficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Endokrinologie in Charlottenburg

    Berlin, State of Berlin, 10627, Germany

  • Haukeland University Hospital

    Bergen, Bergen, 5021, Norway

  • Karolinska Institutet

    Stockholm, Stockholm County, 171 77, Sweden