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Premenstrual dysphoric disorder
MONDO:1010182A severe form of premenstrual syndrome (PMS) that involves significant emotional and physical symptoms in the week or two before a period.
Also known as: PMDD
13 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Wearable Brain-Zapping device aims to ease Period-Related mood and brain fog
Symptom relief Recruiting nowThis study tests a 12-week digital program called Samphire Guided Care for people with menstrual or pelvic health conditions like PMS, endometriosis, or menopause. The program combines a wearable device that gently stimulates the brain, coaching, and symptom tracking to see if it…
Sponsor: Samphire Group, Inc. • Aim: Symptom relief
Last updated Jul 03, 2026 00:00 UTC
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Blood test for PMDD on the horizon? johns hopkins launches biomarker study
Knowledge-focused Recruiting nowThis study from Johns Hopkins aims to find epigenetic markers in blood that could help identify premenstrual dysphoric disorder (PMDD). Researchers will collect blood samples and track mood changes across the menstrual cycle in 500 women — some with PMDD and some without. The goa…
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Scientists probe brain chemistry behind severe PMS to unlock better treatments
Knowledge-focused Recruiting nowThis study looks at how brain chemicals called neuroactive steroids change across the menstrual cycle in women with Premenstrual Dysphoric Disorder (PMDD) compared to healthy women. It also tests whether a low-dose antidepressant (sertraline) affects these chemical levels. The go…
Phase: PHASE4 • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Brain scans and stress tests aim to unravel PMDD vs depression
Knowledge-focused Recruiting nowThis study compares women with PMDD, major depressive disorder (MDD), and healthy controls to see how their brains, stress responses, and inflammation differ. Researchers will use brain scans, stress tasks, and blood/saliva tests in 75 naturally cycling women aged 18-40. The goal…
Sponsor: University Hospital Tuebingen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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25,000 ultrasound scans to train AI for better Women's health diagnosis
Knowledge-focused Recruiting nowThis study is creating a huge collection of ultrasound images from the uterus and ovaries. Researchers will gather scans from 25,000 women, both healthy and with gynecological conditions, during routine checkups. The goal is to build a database that doctors and artificial intelli…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC