Postherpetic neuralgia
MONDO:0041052Also known as: postherpetic neuralgia, PHN - post-herpetic neuralgia, post-zoster neuralgia
38 clinical trials for this condition and its sub-types.
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Shingles nerve block shows promise in preventing chronic pain
Disease control CompletedThis study tested whether an ultrasound-guided nerve block, using a steroid and local anesthetic, could better control pain from shingles and prevent postherpetic neuralgia (long-term nerve pain). 100 adults with acute shingles and moderate to severe pain were randomly assigned t…
Phase: PHASE3 • Sponsor: Assiut University • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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Laser test could objectively measure nerve pain for first time
Diagnosis CompletedThis study tested whether a diode laser can act as a biomarker to measure neuropathic pain in people with peripheral neuropathy. Researchers compared pain responses to a lidocaine patch versus a placebo patch in 75 participants. The goal was to see if the laser test could disting…
Phase: NA • Sponsor: University of Utah • Aim: Diagnosis
Last updated Jun 27, 2026 12:09 UTC
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New shot aims to ease stubborn nerve pain
Symptom relief CompletedThis study tested whether NT 201 injections can reduce pain in adults with long-term nerve pain caused by shingles or a nerve injury. 123 people received either NT 201 or a placebo shot, and researchers tracked their pain levels over 20 weeks. The goal was to see if the treatment…
Phase: PHASE2 • Sponsor: Merz Therapeutics GmbH • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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New drug shows promise for shingles nerve pain
Symptom relief CompletedThis study tested an experimental drug called LX9211 in 79 adults with postherpetic neuralgia, a type of nerve pain that can last for months after a shingles rash heals. The goal was to see if the drug reduces pain and helps with sleep compared to a placebo over 11 weeks. Partici…
Phase: PHASE2 • Sponsor: Lexicon Pharmaceuticals • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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Acupuncture with a jolt: new hope for shingles nerve pain?
Symptom relief CompletedThis completed trial tested whether electroacupuncture (acupuncture with a mild electric current) can reduce pain in people with postherpetic neuralgia, a lingering nerve pain after shingles. 448 adults aged 45-75 with moderate-to-severe pain were randomly assigned to real or sha…
Phase: NA • Sponsor: Nanjing University of Traditional Chinese Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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New shot eases shingles pain that Won't quit
Symptom relief CompletedThis study looked at whether a targeted ultrasound-guided nerve block (SPSIPB) can reduce pain in people with postherpetic neuralgia, a chronic pain condition that can linger after shingles. Researchers reviewed records of 34 adults who received this injection and measured pain l…
Sponsor: Kanuni Sultan Suleyman Training and Research Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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New drug KAI-1678 tested for shingles nerve pain relief
Symptom relief CompletedThis Phase 2 trial tested whether a single dose of KAI-1678 can reduce pain in people with postherpetic neuralgia, a type of nerve pain that lingers after shingles. 23 adults with stable pain levels received either KAI-1678, a placebo, or lidocaine. The main goal was to see if pa…
Phase: PHASE2 • Sponsor: KAI Pharmaceuticals • Aim: Symptom relief
Last updated Jun 26, 2026 13:06 UTC
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Can nerve zapping predict who gets pain relief from shingles?
Knowledge-focused CompletedThis study looked at 77 adults with long-term nerve pain after shingles (postherpetic neuralgia) to see if a spinal nerve stimulation device works better for certain types of pain. Researchers grouped patients by their pain features and measured pain levels, quality of life, and …
Sponsor: Istituti Clinici Scientifici Maugeri SpA • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Shingles nerve pain linked to higher dementia risk in massive study
Knowledge-focused CompletedThis study looked at health records of nearly 69,000 adults aged 40 and older to see if those who develop lasting nerve pain after shingles (postherpetic neuralgia) have a higher chance of getting dementia later. Researchers compared people with and without this nerve pain, match…
Sponsor: China Medical University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Can we predict who gets pain relief from nerve zapping?
Knowledge-focused CompletedThis study reviewed medical records of 60 adults who had radiofrequency treatment for intercostal neuralgia, a type of nerve pain in the chest wall. The goal was to find out which patient or clinical factors are linked to better pain relief after the procedure. Researchers measur…
Sponsor: Mersin University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:14 UTC
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Shingles study aims to predict who gets lingering nerve pain
Knowledge-focused CompletedThis study looked at 151 adults with shingles to find clues that might predict who will develop lasting nerve pain (postherpetic neuralgia). Researchers collected blood samples and health information at the start and checked for pain three months later. The goal was to create a r…
Sponsor: First Affiliated Hospital of Zhejiang University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC