Pneumothorax
MONDO:0002076Abnormal presence of air in the pleural cavity.
Also known as: pneumothorax, pneumothorax (disease)
52 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
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Can a failed ALS drug help PSP patients? new trial results are in
Disease control CompletedThis completed Phase 2b/3 trial tested the drug AMX0035 in 139 people with progressive supranuclear palsy (PSP), a rare brain disease that causes problems with balance, movement, and thinking. The study compared the drug to a placebo to see if it could slow the disease. The resul…
Phase: PHASE2, PHASE3 • Sponsor: Amylyx Pharmaceuticals Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:26 UTC
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Heart surgery breathing study aims to cut lung failure risk
Disease control CompletedThis study tested two ways of managing breathing during heart bypass surgery to see which better prevents lung complications. Over 1,500 adults having planned heart surgery were randomly assigned to either no breathing support or gentle, low-volume breaths while on the heart-lung…
Phase: NA • Sponsor: CMC Ambroise Paré • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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New Light-Measuring tool tested in cancer surgery
Disease control CompletedThis early-phase trial tested a light-measuring system used during photodynamic therapy (PDT) for people with malignant mesothelioma, non-small cell lung cancer, or other pleural cancers. Nine participants received the drug porfimer sodium, which becomes active when exposed to li…
Phase: PHASE1 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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AI matches radiologists in reading chest X-Rays, study finds
Diagnosis CompletedThis study tested an AI tool called Carebot AI CXR to see how well it spots lung problems like collapsed lungs, nodules, and fluid buildup on chest X-rays. Researchers compared the AI's performance to that of human radiologists using 956 patient X-rays. The goal was to see if the…
Sponsor: Carebot s.r.o. • Aim: Diagnosis
Last updated Jun 27, 2026 13:00 UTC
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Could a tiny dose of muscle relaxant make lung scopes safer?
Symptom relief CompletedThis study looked at whether giving a low dose of a muscle relaxant (rocuronium) during bronchoscopy—a procedure where a tube is inserted into the lungs—could reduce complications like throat spasms and coughing. 153 adults having elective bronchoscopy were split into two groups:…
Phase: NA • Sponsor: Harbin Medical University • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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New bedside scanner could detect lung problems in premature babies without X-Rays
Knowledge-focused CompletedThis study tested whether a device called electrical impedance tomography (EIT) can detect collapsed lung (atelectasis) or air leaks (pneumothorax) in newborn babies. Researchers placed the EIT system at the bedside of 20 infants in the NICU and compared its readings to chest X-r…
Sponsor: Sharp HealthCare • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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1200 lung biopsies analyzed: how often do complications occur?
Knowledge-focused CompletedThis completed study looked at 1200 patients who had a CT-guided needle biopsy of a lung nodule at St. Olavs Hospital between 2012 and 2023. The goal was to track how often complications like a collapsed lung (pneumothorax), lung bleeding, or air embolism happen. By analyzing the…
Sponsor: St. Olavs Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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How many biopsies are just right? study aims to improve pleural diagnosis
Knowledge-focused CompletedThis study looked at 104 patients to find the optimal number of tissue samples (biopsies) to take during a pleuroscopy, a procedure to examine the lining of the lungs. The goal was to see how many biopsies are needed to make a diagnosis and to get enough tissue for further testin…
Sponsor: Icahn School of Medicine at Mount Sinai • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Trimmed wire may lower lung collapse risk in nodule removal
Knowledge-focused CompletedThis study looked at over 1,000 patients who had a lung nodule marked with a special trimmed wire before surgery. The goal was to see if this technique raised the risk of a collapsed lung (pneumothorax) compared to using dye alone. Researchers found that the trimmed wire did not …
Sponsor: Chung Shan Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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AI boosts chest X-Ray reading in UK hospital study
Knowledge-focused CompletedThis study tested whether an AI tool called Lunit INSIGHT CXR helps healthcare professionals read chest X-rays more accurately and quickly. Thirty doctors and radiographers reviewed 500 past chest X-rays from two UK hospitals, once with and once without AI help. The goal was to s…
Sponsor: Oxford University Hospitals NHS Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Can lung pressure predict treatment needs in collapsed lung?
Knowledge-focused CompletedThis study measured the pressure inside the chest in 37 adults with a collapsed lung (pneumothorax) who needed a chest tube. Researchers wanted to see if these pressure readings could help predict who would need additional treatments like surgery or a valve. The study was observa…
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC