Platinum-induced ototoxicity

This study looks at whether blood-filtering treatments, such as dialysis or plasma exchange, can help people survive acute poisoning. Researchers will compare over 5,000 poisoned patients who received these treatments with those who did not. The goal is to see if the treatments i…

This study was designed to test whether an oral drug called SPI-1005 could prevent hearing loss and ringing in the ears caused by platinum-based chemotherapy. It was planned for adults with advanced lung or head and neck cancer. The study was withdrawn before enrolling any partic…

This study tests new speech-enhancement software in cochlear implants to help adults with hearing loss understand speech better in noisy places. About 150 adult cochlear implant users will compare the new algorithms to the standard ones. The goal is to see if the new software imp…

This study tests whether an 8-week auditory-cognitive training program can improve speech recognition and cognitive function in older adults (60+) who have had a cochlear implant for 3 months to 3 years. Participants will do computer-based listening and thinking exercises at home…

This study is testing whether hearing aids alone or hearing aids with a tinnitus masker can improve hearing and reduce tinnitus symptoms in adults with hearing loss and tinnitus. One hundred participants will wear hearing aids for 6 months, with the masker turned on after 3 month…

This study looks at whether traditional exercises like Tai Chi and Baduanjin can help people with hearing loss feel better physically and mentally. About 90 adults with severe hearing loss will be split into three groups: one doing Tai Chi, one doing Baduanjin, and one doing regu…

This study looks at whether a special parent training program can help families with deaf or hard of hearing children aged 3 to 6. The program teaches positive parenting strategies to prevent behavior problems. About 295 parents will take part, and researchers will measure change…

This study looks at how stimulating a nerve in the ear affects pupil size during cochlear implant surgery. Researchers will measure pupil dilation in 30 adults to learn more about the vagus nerve's role in hearing. The goal is to gather knowledge, not to treat hearing loss direct…

This study looks at whether managing cochlear implant care remotely (via phone or app) works as well as going to the clinic. About 148 adults with hearing loss will be followed for a year after their implant is activated. The goal is to see if remote care saves time and money whi…