Persistent fetal circulation syndrome
MONDO:0022430A cardiopulmonary disorder characterized by systemic arterial hypoxemia secondary to pulmonary hypertension and extrapulmonary right to left shunting across the foramen ovale and ductus arteriosus.
Also known as: PPHN, persistent fetal circulation, persistent foetal circulation, persistent pulmonary hypertension of the newborn
10 clinical trials for this condition and its sub-types.
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Could a common heart drug save babies with a rare birth defect?
Disease control CompletedThis study looked at whether a medicine called milrinone can improve oxygen levels in newborns with congenital diaphragmatic hernia (CDH), a birth defect that causes severe breathing problems. The trial included 66 babies who were on breathing machines. The goal was to see if mil…
Phase: PHASE2 • Sponsor: NICHD Neonatal Research Network • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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Cord coils linked to fetal heart health in new study
Knowledge-focused CompletedThis study explored whether the number of twists (coils) in the umbilical cord is connected to a baby's heart function during pregnancy. Researchers used ultrasound to measure both the cord coiling and heart function in 202 healthy pregnant women. The goal was to better understan…
Sponsor: Sanliurfa Education and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC