Persistent fetal circulation syndrome
MONDO:0022430A cardiopulmonary disorder characterized by systemic arterial hypoxemia secondary to pulmonary hypertension and extrapulmonary right to left shunting across the foramen ovale and ductus arteriosus.
Also known as: PPHN, persistent fetal circulation, persistent foetal circulation, persistent pulmonary hypertension of the newborn
10 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Fish oil infusion may ease lung pressure in fragile newborns
Disease control ENROLLING_BY_INVITATIONThis study tests whether a special fish-oil emulsion given through an IV can improve outcomes for newborns with a diaphragm defect that causes severe lung pressure. About 40 babies will receive either the fish-oil emulsion or a standard soy-oil one. Researchers will measure lung …
Phase: PHASE2 • Sponsor: Coordinación de Investigación en Salud, Mexico • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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Could a common asthma drug help newborns breathe easier?
Symptom relief OngoingThis phase 3 trial tests whether inhaled salbutamol, a drug used for asthma, can help newborns with transient tachypnoea (rapid breathing after birth). About 608 babies born between 32 and 42 weeks will receive either salbutamol or a placebo. The goal is to see if the drug reduce…
Phase: PHASE3 • Sponsor: Medical University of Warsaw • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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Which oxygen level is best for sick newborns? study aims to find out
Knowledge-focused OngoingThis study looks at two different oxygen level targets for newborns who have trouble breathing or a condition called pulmonary hypertension (high blood pressure in the lungs). About 54 babies born at 35 weeks or later are randomly assigned to one of two oxygen goals. Researchers …
Phase: NA • Sponsor: University of California, Davis • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC