Peptic ulcer disease

This study tests a new medication, linaprazan glurate, to see if it heals esophagus damage from acid reflux better than a standard drug. About 500 adults with erosive esophagitis will take either the new drug or lansoprazole daily for up to 8 weeks. Doctors will use cameras to ch…

This phase 3 study tests two doses of Nexium (esomeprazole) in 53 children aged 1 to 11 years who have erosive esophagitis, a condition where stomach acid damages the esophagus. The goal is to see which dose better maintains healing after an initial 8-week treatment period. Child…

This study was designed to see if a new drug called linaprazan glurate could keep the esophagus healed in people with GERD-related erosive esophagitis, compared to an existing drug (lansoprazole). Participants would have taken daily pills for up to 52 weeks and had regular camera…

This study will follow 5,000 adults who have had endoscopic procedures for weight loss, such as stomach stapling through a scope or gastric balloons. Researchers will track weight, blood pressure, diabetes, and cholesterol for up to 10 years to see how well these procedures work …

This study screens 500 adults in South Florida for H. pylori, a stomach infection that can lead to chronic gastritis, ulcers, and gastric cancer. Those who test positive receive free treatment with a three-drug combination (VOQUEZNA® Triple Pak®) for 14 days. The goal is to see i…

This study screens people in South Florida for H. pylori, a stomach infection that can lead to chronic gastritis, ulcers, and even stomach cancer. Those who test positive receive treatment, and the study compares at-home breath testing versus in-person retesting to confirm the in…

This study tests whether a safe green dye, injected during gastric bypass surgery, can help surgeons see blood flow to the new stomach connection. Poor blood flow can lead to ulcers, leaks, or narrowing. The trial involves 300 adults and will follow them for two years to see if u…

This study was designed to see how well the stomach-acid drug dexlansoprazole is absorbed before and after gastric bypass surgery, and how often ulcers occur afterward. It planned to enroll smokers with obesity who were scheduled for surgery. However, the study was withdrawn befo…

This study tracks 500 adults with conditions like acid reflux, achalasia, or complications after weight-loss surgery. Participants choose either a newer endoscopic procedure (done through a scope) or standard surgery. Researchers will compare how well each approach controls sympt…