Peptic ulcer disease

This phase 3 trial tests whether an experimental drug called DWP14012 (fexuprazan) can heal stomach ulcers as well as or better than the standard treatment lansoprazole. About 384 adults with at least one active gastric ulcer will receive either DWP14012 or lansoprazole daily for…

This study tests whether a simpler two-drug treatment (vonoprazan plus one antibiotic) works as well as a three-drug treatment (vonoprazan plus two antibiotics) for H. pylori infection. About 150 adults with confirmed H. pylori will take either regimen for 14 days. The main goal …

This study looks at whether adding sucralfate (a protective coating agent) to standard esomeprazole (a stomach acid reducer) helps heal artificial ulcers created during endoscopic surgery for early stomach cancer or precancerous growths. About 120 adults will be randomly assigned…

This study looks at whether the drug Fexuclue can prevent stomach ulcers in people who need to take NSAID pain relievers long-term. About 7,000 adults in Korea will take Fexuclue and report their stomach symptoms over 4 weeks. The goal is to see if the drug reduces ulcer symptoms…

This study tests whether a new medicine called Fexuprazan (Fexuclue) can prevent stomach ulcers caused by NSAID painkillers like ibuprofen. About 360 adults with joint or muscle pain who need daily NSAIDs will take either Fexuprazan or an older drug (Lansoprazole) for 24 weeks. T…

This study looks at whether combining a blood test for H. pylori bacteria with a painless stomach ultrasound can predict serious complications from peptic ulcers, like bleeding or a hole in the stomach. Researchers will study 230 adults with stomach symptoms to see if these non-i…

This study looks at whether using a device that helps see veins under the skin can make placing an IV in children faster and with fewer needle sticks. About 500 children under 18 who need an IV for day surgery or other procedures will take part. Researchers will compare the time …