New pill aims to shield stomachs from common painkiller damage

NCT ID NCT07533266

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a new medicine called Fexuprazan (Fexuclue) can prevent stomach ulcers caused by NSAID painkillers like ibuprofen. About 360 adults with joint or muscle pain who need daily NSAIDs will take either Fexuprazan or an older drug (Lansoprazole) for 24 weeks. The goal is to see if Fexuprazan works as well at preventing ulcers and is safe.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Fexuprazan (Fexuclue)

What this could lead to

If it works, this could offer a new option to prevent painful stomach ulcers in people who need long-term NSAIDs for arthritis or similar conditions.

What could go wrong

This is a Phase 4 trial comparing Fexuprazan to an existing drug (Lansoprazole), so it may only show it works as well, not better. The study hasn't started yet, and results may not apply to everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

musculoskeletal system disorder peptic ulcer disease prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Asan Medical Center

    Seoul, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••