New pill aims to shield stomachs from common painkiller damage

NCT ID NCT07533266

Not yet recruiting Prevention Sponsor: Daewoong Pharmaceutical Co. LTD. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a new medicine called Fexuprazan (Fexuclue) can prevent stomach ulcers caused by NSAID painkillers like ibuprofen. About 360 adults with joint or muscle pain who need daily NSAIDs will take either Fexuprazan or an older drug (Lansoprazole) for 24 weeks. The goal is to see if Fexuprazan works as well at preventing ulcers and is safe.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Fexuprazan (Fexuclue)
What this could lead to: If it works, this could offer a new option to prevent painful stomach ulcers in people who need long-term NSAIDs for arthritis or similar conditions.
What could go wrong: This is a Phase 4 trial comparing Fexuprazan to an existing drug (Lansoprazole), so it may only show it works as well, not better. The study hasn't started yet, and results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

musculoskeletal system disorder peptic ulcer disease prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NSAID (NON-STEROIDAL ANTI-INFLAMMATORY DRUG)

Contacts and locations

Locations

Asan Medical Center

Seoul, South Korea

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Other studies related to the condition(s) this trial covers.