Could a simple drug combo speed up stomach ulcer healing after cancer surgery?
NCT ID NCT07312370
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether adding sucralfate (a protective coating agent) to standard esomeprazole (a stomach acid reducer) helps heal artificial ulcers created during endoscopic surgery for early stomach cancer or precancerous growths. About 120 adults will be randomly assigned to get either the combo or esomeprazole alone for 8 weeks. The main goal is to see how much the ulcer shrinks after 4 weeks, and whether the combo reduces bleeding and other complications.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Esomeprazole and sucralfate suspension
- What this could lead to
- If successful, this combination could become a standard treatment to help stomach ulcers heal faster and reduce bleeding after endoscopic surgery for early gastric cancer.
- What could go wrong
- This is a small, early-phase trial with only 120 participants, so results may not apply to everyone. Adding sucralfate may not provide significant benefit over esomeprazole alone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The First Hospital of Lanzhou University
Lanzhou, Gansu, 730000, China
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