Osteochondritis dissecans
MONDO:0017178A rare bone disease characterized by an acquired idiopathic necrotic lesion of subchondral bone with the formation of a sequestrum, which may detach to form loose bodies in joints. OCD mainly affects the knee, ankle and elbow joints and can lead to pain, functional limitations and secondary osteoarthritis.
Also known as: Koenig disease, Konig disease, König disease, OD, osteochondritis dissecans, osteochondritis dissecans (disease), familial osteochondritis dissecans, SSOAOD
19 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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New cartilage patch could help teens with knee damage avoid Long-Term pain
Disease control Recruiting nowThis study tests whether a lab-grown cartilage implant (MACI) works better than a standard surgery (microfracture) for teens aged 10-17 with knee cartilage damage. About 45 participants will receive either treatment and be followed for improvements in pain and sports function. Th…
Phase: PHASE3 • Sponsor: Vericel Corporation • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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Ankle cartilage repair gets a boost: scaffold and stem cells tested in new trial
Disease control Recruiting nowThis pilot study tests a new surgical technique for people with large ankle cartilage and bone defects. Surgeons will drill into the damaged bone and place a scaffold enriched with the patient's own bone marrow cells to help regenerate tissue. The goal is to see if this approach …
Phase: NA • Sponsor: Istituto Ortopedico Rizzoli • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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New hip implant aims to fix cartilage without replacement
Disease control Recruiting nowThis early study is testing a new device called the ReNew Hip Implant in 15 people aged 14 to 64 with hip cartilage damage from conditions like osteoarthritis or hip impingement. The implant is surgically placed to repair the cartilage. Researchers are checking if it is safe and …
Phase: NA • Sponsor: Cytex Therapeutics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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Donor cartilage plugs aim to fix damaged knees
Disease control Recruiting nowThis study tests whether using donated cartilage and bone cores can repair damaged knee cartilage in people aged 12 to 60. The damaged area is replaced with a preserved donor plug. The goal is to see if this improves knee function and reduces pain over time.
Phase: NA • Sponsor: AlloSource • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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Massive 50-Year knee study launches to track OCD outcomes
Knowledge-focused Recruiting nowThis study will follow up to 3000 people diagnosed with osteochondritis dissecans (OCD) of the knee for up to 50 years. Researchers will track how the disease progresses, what treatments people receive, and how their knee function and quality of life change over time. No new trea…
Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:38 UTC
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Knee cartilage repair under the microscope: new study tracks Real-World results
Knowledge-focused Recruiting nowThis study follows 130 adults who had knee cartilage repair surgery to see how their knee function and MRI scans look afterward. Researchers want to collect more data on what happens after these surgeries, since there isn't much information available. Participants will have regul…
Phase: NA • Sponsor: Versailles Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Dissolving screws could save young knees from early arthritis
Knowledge-focused Recruiting nowThis study looks at how well dissolving screws work to fix broken cartilage pieces in the knees of people aged 12 to 35. The goal is to see if this surgery helps prevent long-term problems like pain, stiffness, and early arthritis. Researchers will track symptoms and daily functi…
Sponsor: Istituto Ortopedico Rizzoli • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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New scaffold could help repair knee damage in young adults
Knowledge-focused Recruiting nowThis study is testing a special scaffold designed to help repair damaged knee cartilage in people with osteochondritis dissecans. The scaffold is implanted during surgery to support new tissue growth. Researchers will follow 30 patients aged 15-40 to see how their knee symptoms, …
Sponsor: Istituto Ortopedico Rizzoli • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC