Osteochondritis dissecans
MONDO:0017178A rare bone disease characterized by an acquired idiopathic necrotic lesion of subchondral bone with the formation of a sequestrum, which may detach to form loose bodies in joints. OCD mainly affects the knee, ankle and elbow joints and can lead to pain, functional limitations and secondary osteoarthritis.
Also known as: Koenig disease, Konig disease, König disease, OD, osteochondritis dissecans, osteochondritis dissecans (disease), familial osteochondritis dissecans, SSOAOD
19 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Knee implant shows promise in repairing cartilage damage
Disease control CompletedThis study tested a new implant called Agili-C for people with knee cartilage damage or early arthritis. 251 participants received either the implant or standard surgery. The goal was to see if the implant improved pain and function over 5 years. Results suggest it may be a helpf…
Phase: NA • Sponsor: Smith & Nephew, Inc. • Aim: Disease control
Last updated Jun 27, 2026 08:02 UTC
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Knee cartilage showdown: which surgery wins?
Disease control CompletedThis study compared two surgical methods to repair damaged knee cartilage: a newer cell-based technique (autologous chondrocyte implantation) and a standard bone-graft method (mosaicoplasty). 58 adults aged 18-50 with isolated knee lesions took part. The goal was to see which app…
Phase: PHASE3 • Sponsor: University Hospital, Brest • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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Can Non-Opioid painkillers replace opioids after ankle surgery?
Symptom relief CompletedThis study tested whether a non-opioid pain regimen (celecoxib plus acetaminophen) works as well as an opioid regimen (oxycodone plus acetaminophen) for pain after ankle arthroscopy. 112 adults were randomly assigned to one of the two groups. The goal is to find a safer way to ma…
Phase: NA • Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC