Donor cartilage plugs aim to fix damaged knees

NCT ID NCT06216756

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether using donated cartilage and bone cores can repair damaged knee cartilage in people aged 12 to 60. The damaged area is replaced with a preserved donor plug. The goal is to see if this improves knee function and reduces pain over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

cryopreserved donor cartilage and bone core (osteochondral allograft)

What this could lead to

If successful, this could provide a reliable option for repairing knee cartilage damage, reducing pain and improving mobility without needing a joint replacement.

What could go wrong

This is an early-stage, single-arm study with no comparison group, so results may be less definitive. The graft may not integrate well, and there are risks of infection or graft failure.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

osteochondritis dissecans

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Banner- University Medical Center- Phoenix Orthopedic and Sports Medicine Institute

    RECRUITING

    Phoenix, Arizona, 85006, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Cedars-Sinai Kerlan Jobe Institute

    NOT_YET_RECRUITING

    Los Angeles, California, 90045, United States

    Contact Email: •••••@•••••

    Contact

  • Rush Copley Medical Center

    RECRUITING

    Aurora, Illinois, 60504, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Stanford Medicine-Orthopaedics and Sports Medicine in Redwood City

    RECRUITING

    Redwood City, California, 94063, United States

    Contact Email: •••••@•••••

    Contact

  • University of California San Francisco

    RECRUITING

    San Francisco, California, 94158, United States

    Contact

    Contact Email: •••••@•••••

  • University of Kentucky Research Foundation

    RECRUITING

    Lexington, Kentucky, 40506, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••