Donor cartilage plugs aim to fix damaged knees

NCT ID NCT06216756

Recruiting now Disease control Sponsor: AlloSource Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether using donated cartilage and bone cores can repair damaged knee cartilage in people aged 12 to 60. The damaged area is replaced with a preserved donor plug. The goal is to see if this improves knee function and reduces pain over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: cryopreserved donor cartilage and bone core (osteochondral allograft)
What this could lead to: If successful, this could provide a reliable option for repairing knee cartilage damage, reducing pain and improving mobility without needing a joint replacement.
What could go wrong: This is an early-stage, single-arm study with no comparison group, so results may be less definitive. The graft may not integrate well, and there are risks of infection or graft failure.

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Conditions

The condition(s) this trial relates to.

osteochondritis dissecans

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OSTEOCHONDRAL DEFECT

Contacts and locations

Locations

Banner- University Medical Center- Phoenix Orthopedic and Sports Medicine Institute
RECRUITING

Phoenix, Arizona, 85006, United States
Cedars-Sinai Kerlan Jobe Institute
NOT_YET_RECRUITING

Los Angeles, California, 90045, United States
Rush Copley Medical Center
RECRUITING

Aurora, Illinois, 60504, United States
Stanford Medicine-Orthopaedics and Sports Medicine in Redwood City
RECRUITING

Redwood City, California, 94063, United States
University of California San Francisco
RECRUITING

San Francisco, California, 94158, United States
University of Kentucky Research Foundation
RECRUITING

Lexington, Kentucky, 40506, United States

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