Osteoarthritis, toe
MONDO:0006631Osteoarthritis of the foot generally affects the joint at the base of your big toe. It can cause your toe to: - become stiff over time, which can make it difficult and painful to walk – this is called hallux rigidus - become bent, which can lead to painful bunions (bony lumps at the base of your big toe) – this is called hallux valgus. Osteoarthritis of the mid-foot is also quite common, especially in older people, and may cause an obvious bony swelling (osteophyte) on the top of your mid-foot. Ankle osteoarthritis is least common and may cause your heel to move to an unusual angle.
45 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Can a new shoulder implant restore arm function where others fail?
Disease control Not yet recruitingThis study is following people who receive a Tornier Perform™ Reversed MonoPost shoulder replacement to see how well it works and how safe it is. The implant is designed for patients with severe shoulder damage, such as from arthritis, fractures, or failed previous surgeries. Res…
Sponsor: Stryker Trauma and Extremities • Aim: Disease control
Last updated Aug 16, 2026 00:00 UTC
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Could a simple pill boost knee replacement recovery?
Symptom relief Not yet recruitingThis study tests whether taking tranexamic acid pills for a week after knee replacement surgery helps people recover better. 350 adults having their first knee replacement will receive either the drug or a placebo. Researchers will track pain, stiffness, and function for up to 2 …
Phase: NA • Sponsor: NYU Langone Health • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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Can sound waves boost arthritis shots?
Symptom relief Not yet recruitingThis study tests whether using ultrasound therapy before a steroid injection into the joint can improve pain and swelling for people with arthritis. About 100 adults with arthritis in their arms or legs will receive the combined treatment. The goal is to see if the ultrasound hel…
Phase: NA • Sponsor: Taichung Veterans General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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Could skipping a common additive make numbing shots safer and just as effective?
Symptom relief Not yet recruitingThis study looks at whether leaving out bicarbonate from the numbing medicine (lidocaine with adrenaline) affects how well people recover the day after hand or foot surgery. About 150 adults having common procedures like carpal tunnel release or bunion surgery will be randomly as…
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
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CT scans track hip implant movement to predict Long-Term stability
Knowledge-focused Not yet recruitingThis study tracks 30 people receiving a CATALYSTEM cementless hip implant to measure how much the stem moves (subsides) in the thigh bone over two years. Using specialized CT scans, researchers aim to see if the implant stays firmly in place, which is key for long-term success. P…
Phase: NA • Sponsor: Canadian Radiostereometric Analysis Network • Aim: Knowledge-focused
Last updated Jul 15, 2026 00:00 UTC
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Toe fusion study: can you ski after surgery?
Knowledge-focused Not yet recruitingThis study follows 150 people aged 18-60 who had big toe fusion surgery for hallux rigidus or hallux valgus. Researchers want to see how well patients return to physical activities, especially cross-country skiing, by comparing current sports function to before surgery. Participa…
Sponsor: Oslo University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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New study eyes Tirzepatide's hidden impact on joints and heart
Knowledge-focused Not yet recruitingThis observational study in Mexico will follow 30 adults already taking tirzepatide for conditions like diabetes or obesity. Researchers will use MRI scans of the knees, CT scans of the heart, and body composition tests to see how the drug affects cartilage, heart fat, and overal…
Sponsor: JULIO GRANADOS MONTIEL • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC