Orofacial cleft

This trial compares two speech therapy approaches for Cantonese-speaking children and teens aged 4 to 17 who have cleft palate with or without cleft lip. One method focuses on practicing individual sounds, while the other targets the overall sound system. The goal is to see which…

This study compares two ways to rebuild bone in the gum area of children with a cleft palate. One method uses a custom 3D-printed mold to shape the patient's own bone into a plug, while the other uses small bone chips. The goal is to see which approach fills the bone gap better a…

This study tests whether a nerve block placed in the face can reduce pain and the need for strong opioid drugs after cleft palate surgery in children. The goal is to help kids start eating and drinking sooner and go home faster. The study involves 40 children having cleft palate …

This study planned to test whether a nerve block in the cheek area could reduce the need for morphine after cleft palate repair in children aged 5 months to 12 years. The experimental group would have received the nerve block, while the control group would not. However, the study…

This study looks at whether special high-dissolving foods can improve feeding quality of life for children aged 6 months to 18 years after craniofacial surgery. Half of the 160 participants will receive these foods after surgery, while the other half will follow standard care. Re…

This study aimed to see if using a connected toothbrush (Ara® KOLIBREE) for one month before alveolar bone graft surgery could improve oral hygiene in children aged 5 to 12 with cleft lip and palate. The trial was withdrawn before enrolling any participants, so no results are ava…

This study tests whether a smartphone-based AI tool can help doctors give a pain-blocking injection to babies having cleft lip repair. The goal is to reduce pain during surgery and the need for extra pain medicine. The study includes 120 infants aged 5-18 months and compares the …

This study compares two dental devices—the quadhelix and mini-hyrax expanders—in 24 children with cleft lip and palate who need their upper jaw widened before bone graft surgery. Researchers will use 3D scans and models to measure how much the jaw expands. The goal is to see whic…

This study brings together medical teams that treat children with cleft lip and/or palate. They will collect information on speech, hearing, dental health, and quality of life from about 1,000 patients. The goal is to compare results across centers and find ways to improve care. …