Optic papillitis
MONDO:0006879Swelling of the optic disk, usually in association with increased intracranial pressure, characterized by hyperemia, blurring of the disk margins, microhemorrhages, blind spot enlargement, and engorgement of retinal veins. Chronic papilledema may cause optic atrophy and visual loss. (Miller et al., Clinical Neuro-Ophthalmology, 4th ed, p175)
Also known as: Choked disc, Choked discs, Choked disk, Choked disks, Edemas, optic disc, Edemas, optic disk, decreased intraocular pressure associated papilledema, decreased intraocular pressure-associated papilledema
23 clinical trials for this condition and its sub-types.
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Broader categories
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Could a diabetes drug ease pressure in the brain?
Disease control CompletedThis completed phase 4 trial tested whether a rapid weight loss program using semaglutide (Ozempic/Wegovy) plus a very low calorie diet can help people with idiopathic intracranial hypertension (IIH), a condition where high pressure in the skull causes headaches and vision proble…
Phase: PHASE4 • Sponsor: Rigmor Højland Jensen • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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New eye scanner could sharpen diagnosis of glaucoma and retina diseases
Diagnosis CompletedThis study is testing a new eye imaging device called the VG200D, which uses advanced technology to take detailed pictures of the eye. Researchers want to see if it works as well as a standard device for measuring parts of the eye in people with glaucoma, retina problems, corneal…
Sponsor: Intalight, Inc • Aim: Diagnosis
Last updated Jul 31, 2026 00:00 UTC
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New MRI technique sharpens diagnosis of swollen optic nerve
Diagnosis CompletedThis study looked at whether a new, high-resolution MRI can help doctors more accurately and confidently diagnose the cause of optic disc swelling (a sign of various eye or brain problems). Researchers used these detailed scans on 197 adults with optic disc swelling to see if the…
Sponsor: Fondation Ophtalmologique Adolphe de Rothschild • Aim: Diagnosis
Last updated Jun 27, 2026 08:09 UTC
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AI eye scan could diagnose brain diseases in seconds
Diagnosis CompletedResearchers tested an artificial intelligence program that analyzes retinal images to diagnose several nerve and brain conditions, such as optic neuropathy and brain tumors. The study used data from 693 patients with confirmed diagnoses. The goal is to create a fast triage tool f…
Sponsor: Fondation Ophtalmologique Adolphe de Rothschild • Aim: Diagnosis
Last updated Jun 26, 2026 14:30 UTC
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Soothing sounds: slow music eases anxiety during eye procedures
Symptom relief CompletedThis study tested whether playing slow tempo music before and during an eye injection (intravitreal injection) can reduce anxiety and pain. 144 adults took part, with half listening to music and the other half receiving standard care. Researchers measured anxiety using saliva tes…
Phase: NA • Sponsor: Ng Yu Siang • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
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Built-In eye scanner could give surgeons a live 3D view during operations
Knowledge-focused CompletedThis study tests a microscope that has an OCT scanner built directly into it, allowing surgeons to take detailed cross-sectional images of the eye during surgery. The goal is to see if this setup is practical and whether the extra visual information helps guide surgical decisions…
Sponsor: The Cleveland Clinic • Aim: Knowledge-focused
Last updated Aug 05, 2026 00:00 UTC
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New eye scanner aims to sharpen view of retinal disease
Knowledge-focused CompletedThis trial tests a new device called P200TxE that takes detailed images of the back of the eye. Researchers want to see how well it captures images in people with retinal diseases like glaucoma or macular degeneration. The study involves adults aged 22 and older who have been dia…
Phase: NA • Sponsor: Optos, PLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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AI boosts eye Doctors' accuracy in reading retinal scans?
Knowledge-focused CompletedThis study tested whether artificial intelligence (AI) can help doctors detect retinal diseases from ultra-widefield eye images. 462 images were read by four eye doctors with different experience levels, both with and without AI assistance. The goal was to see if AI improves accu…
Sponsor: Xiamen Ophthalmology Center Affiliated to Xiamen University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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MRI contrast dye may skew brain scans, study finds
Knowledge-focused CompletedThis study looked at how gadolinium, a dye used in MRI scans, changes the QSM signal in the brain's white matter. 73 patients with inflammatory central nervous system conditions had MRI scans before and after receiving gadolinium. The goal was to measure any differences in the si…
Sponsor: Fondation Ophtalmologique Adolphe de Rothschild • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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MRI scans reveal hidden brain drains in rare headache disorder
Knowledge-focused CompletedThis study looked at the brain's lymphatic system in 40 women with idiopathic intracranial hypertension (IIH), a condition causing severe headaches and vision loss. Researchers used a special MRI technique to compare lymphatic vessels in patients and healthy controls. The goal wa…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC