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Ocular toxoplasmosis

MONDO:0005879

Ocular toxoplasmosis is an infection in the eye caused by the parasite, Toxoplasm a gondii. Toxoplasmosis is the most common cause of eye inflammation in the world. Toxoplamosis can beacquired or present at birth (congenital), having crossed the placenta from a newly infected mother to her fetus. Most humans acquire toxoplasmosis by eating raw or undercooked meat, vegetables or milk products, or by coming into contact with infected cat litterbox or sandboxes.In humans,the infectionusually causes no symptoms, and resolves without treatment in a few months. In individuals with compromised immune systems, Toxoplasm a gondii can reactivate to cause disease. Reactivation of a congenital infection was traditionally thought to be the most common cause ofocular toxoplasmosis, but an acquired infection is now considered to be more common. A toxoplasmosis infection that affects the eye usually attacks the retina andinitially resolves without symptoms. However,the inactive parasite maylaterreactivate causing eyepain, blurred vision, and possibly permanent damage, including blindness. Although most cases of toxoplasmosis resolve on their own,for some,inflammation can be treated with antibiotics and steroids.

36 clinical trials for this condition and its sub-types.

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Broader categories

Disease (618) Infectious disease (270) Eye disorder (97) Human disease (14) Parasitic infectious disease (10) Eye infectious disorder (4) Toxoplasmosis (4) Disorder of orbital region (3) Protozoa infectious disease (2) Disorder of visual system (1)
Trials to join now! 21 Not yet recruiting 5 Not yet finished but already full! 4 Completed 4 Terminated 2
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