Can the Body's own 'Off Switch' for inflammation predict who survives severe infection?
NCT ID NCT07353970
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study will follow 300 adults with severe infections in the ICU to see how levels of specialized pro-resolving mediators (SPMs)—natural molecules that help stop inflammation—change over time. Researchers will use blood samples already collected during routine care, so no extra tests or treatments are given. The goal is to find patterns that could help doctors identify high-risk patients earlier and improve care.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could help doctors identify high-risk patients with severe infections earlier, potentially guiding more personalized care.
What could go wrong
This is an observational study, not a treatment trial. It will not directly test any new drug or therapy, and results may not lead to immediate changes in patient care.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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