Which antibiotic combo is safer for your kidneys? new trial aims to find out

NCT ID NCT07556107

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two common antibiotic combinations—vancomycin with piperacillin/tazobactam versus vancomycin with meropenem—to see which is less harmful to the kidneys. About 852 hospitalized adults with serious infections will be randomly assigned to one of the two combos. The goal is to help doctors make safer treatment choices.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

vancomycin combined with either piperacillin/tazobactam or meropenem

What this could lead to

If it works, this could help doctors choose the safer antibiotic combination to reduce kidney damage in hospitalized patients.

What could go wrong

This is a Phase 4 trial comparing already-approved drugs, so no major breakthrough is expected. Results may show no clear difference or may not apply to all patient groups.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute kidney injury Infections infectious disease infectious disease with sepsis Sepsis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Bassett Medical Center

    Cooperstown, New York, 13326, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••