Neuroma

This study tests if botulinum toxin (like Botox) provides longer-lasting pain relief than a standard numbing injection for people with chronic nerve pain after losing a limb in combat. About 100 adults with confirmed nerve pain will get one of the two injections and be tracked fo…

This study compares two injection treatments for chronic nerve pain (neuroma) after combat-related amputation. One uses platelet-rich plasma (PRP) from the patient's own blood, the other uses a standard local anesthetic. About 100 adults with persistent pain will receive an ultra…

This study looks at two ways to inject botulinum toxin (like Botox) to treat long-term nerve pain from amputation in 100 combat veterans. The goal is to see which method—injecting inside the nerve or around it—works better for reducing pain and improving daily life. Participants …

This study tests two ways to freeze painful nerve endings (neuromas) in people who lost limbs in combat. One method freezes the nerve right at the painful spot, the other freezes it further up the nerve. The goal is to see which provides better pain relief. Fifty adults with chro…

This study tests whether taking N-acetylcysteine (NAC), a common supplement, before and after hand or foot surgery can reduce pain and the need for opioid painkillers. About 80 adults will be randomly assigned to take NAC or a placebo for 14 days. Researchers will track pain, fun…

This study will compare two surgical techniques for treating pain after a finger amputation: reconnecting the nerve (microanastomosis) versus cutting and burying it (traction neurectomy). Researchers will track pain levels and hand function in 50 adults over six months. The goal …