Freezing away phantom pain: new study tests two Nerve-Freezing techniques for amputees

NCT ID NCT07618689

Not yet recruiting Symptom relief Sponsor: Ukrainian Society of Regional Anesthesia and Pain Therapy Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests two ways to freeze painful nerve endings (neuromas) in people who lost limbs in combat. One method freezes the nerve right at the painful spot, the other freezes it further up the nerve. The goal is to see which provides better pain relief. Fifty adults with chronic neuroma pain will be enrolled, and their pain levels will be tracked over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: cryoablation (freezing nerve tissue)
What this could lead to: If it works, this could point toward a better way to manage stubborn nerve pain after amputation, improving mobility and quality of life.
What could go wrong: This is a small, early-stage study with only 50 participants, so results may not apply widely. Cryoablation may not provide lasting pain relief, and nerve damage could cause new symptoms.

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Conditions

The condition(s) this trial relates to.

neuroma Peripheral Nerve Injuries Phantom Limb Wallerian degeneration

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CRYOABLATION NEUROMA

Contacts and locations

Locations

Vinnitsya university hospital

Vinnytsia, Вінницька, 21000, Ukraine

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