Nematoda infectious disease

This large Phase 3 trial compared the safety of a single dose of moxidectin versus ivermectin in nearly 13,000 people living in areas where river blindness is common. Some participants also received albendazole for lymphatic filariasis. The goal was to see if moxidectin causes fe…

This study tested whether higher doses of ivermectin, combined with albendazole, are safe and effective for treating whipworm infections in children aged 2 to 5 years. The trial involved 260 children in Tanzania and compared different doses of ivermectin, including a new dissolva…

This study tested whether combining two drugs—moxidectin and albendazole—works better than albendazole alone for treating whipworm infections in children aged 6 to 12. The trial took place in Tanzania and involved 224 children. Researchers measured how many children were cured an…

This study tested a single dose of moxidectin in 36 children aged 4 to 17 who have or are at risk of onchocerciasis (river blindness). The goal was to find a dose for children 4-11 years that works like the standard 8 mg dose used in older kids and adults. Researchers measured dr…

This study looked at three different blood tests (ELISA) for diagnosing strongyloidiasis, an infection caused by a parasite that can stay hidden in the body. Researchers tested 80 adult patients who had previously had a positive or borderline result. The goal was to see which tes…

This completed study looked at how common fish allergy is among people who work with fish, like fishermen and fish-processing factory workers, compared to other workers. Researchers surveyed 486 people in Boulogne-sur-Mer, France, asking about allergic symptoms and exposure to fi…