New combo drug doses aim to wipe out whipworm in toddlers

NCT ID NCT06184399

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tested whether higher doses of ivermectin, combined with albendazole, are safe and effective for treating whipworm infections in children aged 2 to 5 years. The trial involved 260 children in Tanzania and compared different doses of ivermectin, including a new dissolvable tablet. The main goal was to see how many children were cured of the infection after treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
ivermectin and albendazole
What this could lead to
If successful, this could point toward a more effective treatment for whipworm infections in young children, reducing the burden of this parasitic disease.
What could go wrong
This is a Phase 2 dose-ranging trial with 260 children, so results are preliminary. The treatment may not prove more effective than current options, and side effects are possible.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Public Health Laboratory Ivo de Carneri

    Chake Chake, Tanzania

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